Fresenius Medical Care Holdings, Inc.

Cheryl Ford

Jiunn Teo

Leslie Schmidt

Harold Frederick Sandford

Benjamin J Lipps

Norma J Ofsthun

Amanda K Stennett

Michael James Beiriger

Geoffrey Russell

Kevin Hudson

James White

Selvaraj Savariar

Brett Allen Barton

Geoffrey Andrew Russell

Selvaraj (deceased) Savariar

Jiunn Yeong Teo

Harold F Sandford

The present invention relates to the use of additives in processes to form polymeric fibers. These fibers can be formed into membranes with improved middle and/or higher molecular weight solute removal.

Performance enhancing additives for fiber formation and polysulfone fibers

A process for making polyarylethers provides a reaction mixture that includes a dipolar aprotic solvent for polyarylether and polyarylether forming reactants, and reacts the polyarylether-forming reactants, with removing of water with nitrogen in the absence of azeotrope forming cosolvent and optionally replacing removed amounts with dipolar aprotic solvent. The process can further include directly wet spinning the reactor solution without recovery of the polymer from the dipolar aprotic solvent through a spinneret to form hollow fibers or flat sheets suitable for membranes.

Process for making polyarylethers and use in membrane preparation

A dialysate regeneration system for removing contaminants from spent dialysate according to this invention includes a dialysate circulation flow path including a pump that pumps spent dialysate through the dialysate circulation flow path, a first cartridge adapted to remove contaminants from the spent dialysate, including a first cleaning solution inlet and a first cleaning solution outlet, a second cartridge adapted to remove urea from the spent dialysate, the second cartridge including semi-permeable hollow fibers adapted for transport of urea across the walls of the semi-permeable hollow fibers and adapted to retain at least calcium, magnesium, and sodium ions in the spent dialysate, and including a second cleaning solution inlet and a second cleaning solution outlet. Ancillary to the two cartridges, the dialysate regeneration system further includes a first dialysate cleaning flow path including a pump that pumps first cleaning solution from the first cleaning solution outlet of the first cartridge through a first cleaning stage to the first cleaning solution inlet of the first cartridge, and a second dialysate cleaning flow path including a pump that pumps second cleaning solution from the second cleaning solution outlet of the second cartridge through a second cleaning stage to the second cleaning solution inlet of the second cartridge.

Peritoneal dialysis system

A portable peritoneal dialysis system for a patient includes an inlet port for providing inflow to the patient's peritoneal cavity, an outlet port for providing outflow from the patient's peritoneal cavity, and a volume of dialysate for flow into and out of the patient's peritoneal cavity, thereby removing from the dialysate uremic waste metabolites that have diffused into the dialysate. The portable peritoneal dialysis system also includes a closed liquid flow loop, including a pump, for flowing the dialysate into and out of the patient's peritoneal cavity, and an organic- and phosphate-removing stage, including at least one replaceable cartridge in the closed liquid flow loop, the cartridge containing material for removing organic compounds and phosphate from dialysate removed from the patient's peritoneal cavity. The portable peritoneal dialysis system further includes a urea- and ammonia-removing stage, including at least one replaceable cartridge in the closed liquid flow loop, the cartridge containing material for removing urea and ammonia from dialysate removed from the patient's peritoneal cavity, the material being packed around semi-permeable hollow fibers with interior fiber walls that reject cations, thereby retaining cations in the dialysate.

Portable peritoneal dialysis system

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Ogden, UT, United States of America

Cheryl Ford