Korea Institute of Science and Technology

Republic of Korea (management: Rural Development Administration)

Cheol-Ho Pan

Yongsoo Choi

Sang Min Kim

Byung Hun Um

Joo Young Lee

Man Soo Choi

Sang Hoon Jung

Chu Won Nho

Sungdo Ha

Eun Ha Lee

Jin-Chul Kim

Hee Ju Lee

Kyungsu Kang

Kwang-Hyun Cha

Kyung Su Kang

Saet Byoul Lee

Jung Kyung Moon

Soo Kwon Park

Hong Ryul Ahn

Nam Hee Jeong

Na Ra Jeon

Sung Taeg Kang

Ji Hye Yoo

Soon Chun Jeong

Suk Woo Kang

Jeongsook Shin

Dae-Geun Song

Jung-Seok Yang

Kyung A Kim

Sang Moo Kim

Song Yi Koo

Keunwan Park

Hyoung Seok Kim

Bok-Kyu Shin

Erdenedolgor Erdene-Ochir

Jae-In Eom

Provided is a pharmaceutical composition, a health food composition, or a quasi drug composition for preventing, treating, or improving a disease caused by overproduction of dihydrotestosterone, including fucoxanthin or aextract as an active ingredient.

Composition for preventing or treating disease caused by overproduction of dihydrotestosterone comprising fucoxanthin

Provided are a seed of new soybean cultivar SCEL-1, a plant body of the seed or a part of the plant body, and an extract obtained from the seed.

Seed of new soybean cultivar SCEL-1, plant body of the seed and part of the plant body, and extract obtained from the seed

Provided is an amine group-derivatized composition including a Boc compound for liquid chromatography-mass spectrometry (LC-MS) analysis, and when the amine group-derivatized composition is used in analysis using reverse-phase LC-MS, it is possible to effectively analyze compounds including an amine group and an amino acid at a low cost in a short time.

Method of analyzing compound including amine group by using Boc compound

The present invention relates to a method for the prevention and treatment of postmenopausal syndrome containing the step of administering a pharmaceutically effective dose of theor its fractions to a subject. The present inventors confirmed that theextract or its fractions of the invention prepared by using water, alcohol or a mixed solvent thereof could promote the expression of the promoter containing estrogen responsive element (ERE) and accelerated the growth of MCF-7, the human breast tissue originated cell line, suggesting that they had estrogen activity. The inventors further confirmed that the extract or its fractions of the invention had the effect of promoting osteocyte differentiation, so that they could be effectively used for the prevention and treatment of postmenopausal syndrome such as hot flush, osteoporosis and phlebothrombosis caused by estrogen deficiency.

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The present invention relates to a signal sequence peptide for the improvement of extracellular secretion efficiency of a heterologous protein in. More particularly, the present invention relates to a gene construct for the improvement of extracellular secretion efficiency of the said heterologous protein in, which comprises a polynucleotide encoding a recombinant protein composed of the heterologous protein linked to C-terminal of the signal sequence peptide represented by SEQ. ID. NO. 3. The present invention contributes to the improvement of extracellular secretion efficiency of a recombinant protein, so that it can be effectively applied to the production of a recombinant protein.

Growing community of inventors

Gangneung-si, South Korea

Cheol-Ho Pan