University of Pennsylvania

Thomas Jefferson University

Chengyuan Wu

Brian Litt

Justin Blanco

Ankit N Khambhati

Allan Azarion

Joost Wagenaar

Jue Wu

Ashwini D Sharan

The subject matter described herein relates to methods, systems, and computer readable media for visualization of a resection target during epilepsy surgery and for real time spatiotemporal visualization of neurophysiologic biomarkers. One exemplary method includes a real time neurophysiologic biomarker visualization system implemented by at least one computer, receiving, as input, a pre-electrode-implantation MRI of an epilepsy patient's brain.

Methods, systems, and computer readable media for visualization of resection target during epilepsy surgery and for real time spatiotemporal visualization of neurophysiologic biomarkers

In accordance with one embodiment, a device for performing an angled craniotome includes an elongate handle, a footplate, a stem, and an elongate cutting bit. The elongate handle extends in a vertical direction. The footplate is spaced apart from the elongate handle and defines a plane generally perpendicular to the vertical direction. The footplate is offset from the handle in a horizontal direction where the horizontal direction is perpendicular to the vertical direction. The stem has a proximal end and a distal end. The proximal end is coupled to the handle and the distal end is coupled to the footplate. The stem extends from the handle at an oblique angle in the horizontal direction relative to the handle. The elongate cutting bit is coupled to the handle and extends from the handle toward the footplate at the oblique angle in the horizontal direction relative to the handle.

Angled craniotome and minimal plating system for improved cosmesis and structural integrity of craniotomies

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Merion, PA, United States of America

Chengyuan Wu