Geneblue Corporation

Chengqiu Wang

Xiaozhuang Bian

Mi He

Dexian Dou

Chromatin peptide drug molecules, which can block human cell hypoxia responsive pathway, are DNA affinity structural domain of related transcription genes or their imitating molecules or derivatives, containing 5-100 amino acid residues which can specifically bind firmly to HIF-1&#x3b1; gene self promoter or its downstream regulated more than 40 gene promoters. The above-mentioned molecules can permanently shut down molecular pathway including cell glucolysis reaction, immuno-inflammation reaction or hypoxia response, thus sustained stop uncontrollable proliferation of later stage tumor cells or chronic inflammation cells in the condition of hypoxia.

Growing community of inventors

Tianjin, China

Chengqiu Wang