Industrial Technology Research Institute

Hon Hai Precision Industry Co., Ltd.

Hong-fu Jin Precision Industry (shenzhen) Co., Ltd.

Cheng-Tao Wu

Chao-Chi Pan

Jia-Huey Tsao

Wen-Hsun Kuo

Chih-Wei Ho

Yao-Sung Chang

Zu-Sho Chow

Bor-Iuan Jan

Yu-Ching Liu

Chung-Cheng Liu

Yu-Ching Chang

Yu-Yu Lin

Shiu-Chieh Lan

Yi-Fang Wu

Ya-Ni Zhang

Yen-Ju Lin

Kai-Yuan Lin

Bor-Iaun Jan

Chang-Yi Lu

Meng-Tsung Tien

Cong Cao

Yih-Huei Uen

The disclosure relates to a method for determining incidence of liver cancer in a subject, including detecting methylation level or expression level of one microRNA miR-129-2 in a bio-sample from the subject. In the case that the methylation level of the microRNA in the bio-sample is higher or the expression level of the microRNA in the bio-sample is lower relative to that of the corresponding microRNA in a control sample, indicates that the subject is predisposed to or afflicted with liver cancer.

Biomarker for human liver cancer

Provided herein is a method for detection of migratory and invasive cancer cells based on a number of marker nucleic acids differentially expressed in migratory/invasive cancer cells relative to nonmigratory/noninvasive cancer cells. Also disclosed are antisense oligonucleotides of the marker nucleic acids and uses thereof for suppressing cancer cell migration and invasion.

Oligonucleotides for suppressing cancer cell invasion and migration

A connector mounting apparatus includes a mounting bracket and a receiving member. A receiving space is defined in the mounting bracket. The receiving member includes a main body, a first resilient resisting tab extending outward from a base panel of the main body, and a first resilient contacting tab extending inward from the base panel to resiliently abut a connector interface received inside the main body. The main body is received in the receiving space and the first resisting tab resiliently abuts an inner surface of the receiving space.

Connector mounting apparatus having a bracket with recesses abutting resisting tabs of a member received therein

Disclosed are methods of identifying microRNA motifs or microRNA precursors for a target gene or a set of target genes. Also disclosed are related computer-readable media.

MicroRNA precursors

MicroRNA motifs

The invention discloses an on-spot hydrophilic enhanced slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing functional groups such as anhydride, imide, cyclic amide, and cyclic ester, and application of the hydrophobic copolymer onto an organic or inorganic substrate. The resulting slide has the properties of on-spot hydrophilic/hydrophobic dynamic conversion, as well as on-spot hydrophilic enhancement for the preparation of high-density and high-efficiency bio-chip/microarray.

On-spot hydrophilic enhanced slide and preparation thereof

The invention features a method for preparing a high-density functional slide by coating a sol-gel containing amine-group bearing silanes and a solution containing polyaldehyde groups onto an organic or inorganic substrate, respectively. The resulting slide is useful in the preparation of highly homogeneous functional-group slides and the high-density and high-efficiency bio-chip/microarray.

High-density functional slide and preparation method thereof

A method is provided for preparing an active slide, including introducing a monomer containing an aldehyde group, or a mixture of a monomer containing an aldehyde group and an acidic functional group provider into a plasma chamber; and depositing the aldehyde group and acidic functional group onto the surface of an organic or inorganic matrix using plasma deposition to form a slide comprising a layer of polymerized actively functional groups thereon. The aldehyde groups and negatively charged groups are deposited on the surface of the active slide, such that the bio-molecules bound thereto possess the properties of an inducible orientation and thus form a mono-layer.

Activated inorganic slide having aldehyde groups deposited by plasma deposition

Growing community of inventors

Tainan, Taiwan

Cheng-Tao Wu