Neurocrine Biosciences, Inc.

Other

Adobe, Inc.

Boehringer Ingelheim International Gmbh

Abm Therapeutics Corporation

Saphlux, Inc.

Chen Chen

Zhiqiang Guo

Fabio C Tucci

Charles Q Huang

Martin W Rowbottom

James R McCarthy

Dongpei Wu

Yun-Fei Zhu

Keith M Wilcoxen

Warren Stanfield Wade

Timothy David Gross

Thomas R Webb

Yongsheng Chen

R Scott Struthers

Terence J Moran

Wesley J Dwight

Patrick J Connors

Jue Wang

Mustapha Haddach

Jaimie Karyn Rueter

Joe Anh Tran

Jane Elizabeth Hoffswell

Yinghong Gao

Ryan A Rossi

Jeffrey Paul Whitten

Eunyee Koh

Trung Huu Bui

Jennifer Anne Healey

Fan Du

Brian Dyck

Timothy Richard Coon

Junko Tamiya

Neil Ashweek

Troy Vickers

Joseph Pontillo

Cuong D Nguyen

Nicole Harriott

Jie Song

Shunan Guo

Collin Regan

Nathan Carl Ross

Florence Jovic

Mustapha Hadduch

John Y Ramphal

Yun Feng Xie

Yeuk Yin Chan

In some embodiments, methods for fabricating micro-LEDs may include bonding a semiconductor wafer to a Complementary Metal-Oxide-Semiconductor (CMOS) wafer via one or more adhesive layers, etching the LED epilayer and the one or more adhesive layers to form a plurality of micro-LED structures, and fabricating an electrode layer on the plurality of micro-LED structures. The semiconductor wafer may include an LED epilayer including an n-GaN layer, a p-GaN layer, and an active layer positioned between the n-GaN layer and the p-GaN layer. Prior to the bonding of the semiconductor layer to the CMOS wafer, a stress release pattern may be formed in the LED epilayer. The stress release pattern may include a plurality of geometrical shapes (e.g., squares, rectangles, hexagons, rings, etc.) that may facilitate the release of mechanical stresses induced during the subsequent processing of the semiconductor wafer and/or the fabrication of the micro-LEDs.

Mechanisms for fabricating micro-LEDs

In some examples, an augmented reality (AR) server receives instructional data to be rendered in AR. The AR rendering server extracts multiple instruction steps from the instructional data and determines multiple spatial identifiers associated with the multiple instruction steps respectively. The multiple spatial identifiers correspond to multiple spatial objects in a real-world environment. The AR rendering server then generates AR rendering data for displaying the multiple instruction steps on an AR device at selected locations associated with the multiple spatial objects in the real-world environment. The AR rendering data is then transmitted to the AR device.

Rendering and anchoring instructional data in augmented reality with context awareness

Systems and methods for data analysis are described. Embodiments of the present disclosure data analysis include displaying, via a data analysis interface, a data visualization in a first region of the data analysis interface; and displaying, via the data analysis interface, an analysis thread visualization in a second region of the data analysis interface. The analysis thread visualization depicts an analysis thread graph including a first node corresponding to the data visualization and an edge corresponding to an analysis path between the first node and a second node.

Generating data insights

Provided are cyclic iminopyridimdine compounds and their bicyclic derivatives, pharmaceutical compositions comprising such compounds, and methods of using such compounds or compositions, such as methods of treating a proliferation disorder, such as a cancer or a tumor, or in some embodiments disease or disorders related to the dysregulation of kinase such as, but not limited to B-Raf V600E kinase.

Cyclic iminopyrimidine derivatives as kinase inhibitors

Methods and systems for dehazing images with increased accuracy and reduced error enhancement. In particular, one or more embodiments estimate a transmission map representing an amount of unscattered light reflected from objects in an input image. One or more embodiments refine the transmission map to obtain transmission information consistent with a depth of the objects in the input image. One or more embodiments also determine a radiance gradient for the input image. One or more embodiments generate an output image from the input image by removing haze based on the refined transmission map and preventing error enhancement based on the determined radiance gradient.

Dehazing photos and videos using visual artifact suppression

New compounds are disclosed which have utility in the treatment of a variety of metabolic related conditions in a patient. The compounds of this invention have the structure (I): wherein X, X, X, X, Y, Y, A, R, R, R, R, m, n, p, and q are as defined herein, including stereoisomers, esters, and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof in a patient in need thereof.

Compounds, pharmaceutical composition and methods relating thereto

New compounds are disclosed which have utility in the treatment of a variety of metabolic related conditions in a patient. The compounds of this invention have the structure (I): wherein R, R, R, n, p, q, and Ar are as defined herein, including stereoisomers, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising a compound of this invention, as well as methods relating to the use thereof in a patient in need thereof.

GnRH receptor antagonists are disclosed that have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, Q, R, R, R, R, R, R, Rand n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.

Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

GnRH receptor antagonists are disclosed that have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R, R, R, R, R, R, R, R, Rand X are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.

Gonadotropin-releasing hormone receptor antagonists and methods related thereto

GnRH receptor antagonists are disclosed that have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein n, R, R, R, R, R, R, R, R, Rand X are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.

GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, R, R, R, R, R, R, R, and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.

Growing community of inventors

San Diego, CA, United States of America

Chen Chen