Samyang Corporation

Samyang Biopharmaceuticals Corporation

Sam Yang Co., Ltd.

Chaul-Min Pai

Min-Hyo Seo

Seung-Jin Lee

In-Ja Choi

Guw-Dong Yeo

Kyung-Hee Kim

Sujung Lee

Sung-Chul Kim

Jong-Pyoung Jung

Seok-Joon Yoon

You-Chan Kim

Jae-Yong Lee

Jee-Hyang Kim

Bo-Youn Seo

Seung-Seo Lee

Sung-Bum La

Chang-Baeg Lim

Eun-Ok Chang

In-Suk Song

Su-Jong Hwang

Jun-Seok Hwang

Hyun-Ki Lee

Mi-Hong Min

Kyung-Mi Cho

A poorly soluble drug containing microsphere with improved bioavailability, an oral formulation comprising the same, and a method of preparing the same are provided, wherein the poorly soluble drug containing microsphere is a solid dispersion wherein the poorly soluble drug is dispersed in the water-soluble polymer carrier in a noncrystalline form by spray drying, thus increasing bioavailability of the poorly soluble drug.

Poorly soluble drug containing microspheres with improved bioavailability and method of preparing the same

A biodegradable polymeric drug carrier micelle composition capable of solubilizing a hydrophobic drug in a hydrophilic environment comprises a biodegradable polymeric drug carrier micelle and a hydrophobic drug wherein the drug is physically trapped within and not covalently bonded to the polymeric drug carrier micelle. The drug carrying micelle is capable of dissolving in water to form a solution thereof, and the drug carrier comprises an amphiphilic block copolymer having a hydrophilic poly(alkylene oxide) component, and a biodegradable hydrophobic polymer component selected from the group consisting of poly(lactic acid), poly(glycoloc acid), poly(lactic-co-glycolic acid), poly(&egr;-caprolactone), a derivative thereof and a mixture thereof. Preferably the amphiphilic block copolymer has a molecular weight in a range of about 1430 to about 6000 Daltons and the hydrophilic component content is in a range of about 50 wt % to about 70 wt % based on the total weight of the block copolymer.

Biodegradable polymeric micelle-type drug composition and method for the preparation thereof

A composition comprising gelatin and a polysaccharide which is degradable by a colonic enzyme and, optionally, with an aldehyde and/or a polyvalent metal ion and/or an additional polysaccharide, which is not degraded or disintegrated in the upper gastrointestinal tract, thereby rendering the active substance loaded therein to be selectively delivered to the colon and to be effectively released in the colon.

Colon selective drug delivery composition

Locally administrable, biodegradable and sustained-release pharmaceutical composition for periodontitis and process for preparation thereof

An implantable bioresorbable membrane for the separation and regeneration of tissue in a defect site and augmentation of tissues surrounding other implants comprises: (a) porous bioresorbable polymer matrix made of a bioresorbable polymer selected from the group consisting of polylactic acid, poly(lactic-co-glycolic acid), polycarprolactone, polyparadioxanone, polytrimethylene carbonate and a mixture thereof; and (b) a reinforcing fabric made of bioresorbable fibers embedded in said matrix, and is produced by preparing a fabric as a support from bioresorbable fibrous materials, coating the fabric with a solution containing a bioresorbable polymer and a pore forming agent, and treating the coated fabric to generate pores.

Implantable bioresorbable membrane and method for the preparation thereof

Growing community of inventors

Taejeon, South Korea

Chaul-Min Pai