Howmedica Osteonics Corporation

Stryker European Holdings I LLC

Stryker European Operations Holdings LLC

Chau Ngo

Philip F Williams, Iii

Robin Stamp

Steven Willis

Paul Higham

Justyna Zielinska

Christopher DeMaria

Lewis Mullen

John Lapszynski

Robert Carter

Richard Wood

Aiguo Wang

Matthew P Poggie

Nicholas Nai Guang Dong

Robert W Klein

Marc Esformes

Philip F Iii Williams

A bone part is repaired by a process. A first implant is attached to a first bone part. The first implant corresponds to an intraoperatively defined or an intraoperatively selected cutting path. A preoperatively defined second implant is attached to the first implant. The first implant and the second implant together augment the first bone part.

Augmented, just-in-time, patient-specific implant manufacture

A spinal implant including porous and solid portions is disclosed. The implant includes porous portions on upper and lower surfaces and in an interior thereof. Methods of manufacturing and implanting such implants are also disclosed.

Spinal implant with porous and solid surfaces

Porous tibial implant

A spinal implant for replacing the natural nucleus of the disc made from a polymer such as hydrogel having a radiopaque material located within the polymer. The material may be in the form of a powder dispersed throughout the polymer or may be in he form of a powder dispersed in layers or in other specific locations within the polymer. The radiopaque material is metal such as gold, tungsten, titanium, tantalum or platinum. The metal may also be in the form of a foil or wire located within the hydrogel such as polyurethane, thereby making the implant visible on x-rays. Other polymers besides hydrogel may be used with the radiopaque material being dispersed therein.

Radiovisible hydrogel intervertebral disc nucleus

A high strength hydrogel having a constant swelling pressure upon implantation and thereafter is formed by preparing a hydrogel solution and then injecting the solution into a mold and cause to gel. The molded gel is then washed in a saline solution from about one day to twelve weeks, after which the gel is irradiated for sterilization purposes, dehydrated and packaged. The pre-treatment with the use of a physiologic solution results in an implant which exhibits a constant swelling pressure profile after implantation.

Ion treated hydrogel

A wear resistant hydrogel for use as a prosthetic implant, such as for cartilage, is made by forming a solution of polyvinyl alcohol in a solvent of DMSO/water. The solution is placed in a mold and is gelated by cycling the mold in a freeze-thaw cycle at a temperature at or below 4&#xb0; C. for a period of 2 to 24 hours. The hydrogel so formed is washed in a saline solution, including potassium carbonate. The hydrogel is then dehydrated to 20 to 70% water content and thereafter irradiated with Gamma radiation. The surface of the hydrogel is then cross-linked using a boric acid solution preferably between 2.5 and 5% for about 1 minute. The hydrogel is then rinsed and sterilized.

Wear resistant hydrogel for bearing applications

Method of making an ion treated hydrogel

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Secaucus, NJ, United States of America

Chau Ngo