Centre National De La Recherche Scientifique

Graftys

Université De Nantes

Oniris

University De Nantes

Ecole Nationale Veterinaire Agroalimentaire Et De L'alimentation Nantes Atlantique

Charlotte Mellier

Bruno Bujoli

Jean-Michel Bouler

Pascal Janvier

Olivier Gauthier

Ibrahim Khairoun

Verena Schnitzler

A bone cement paste containing a powder component comprising &#x3b1;-tricalcium phosphate (&#x3b1;-TCP) particles having an average size greater than or equal to 9 &#x3bc;m, and a liquid component comprising blood is disclosed. A method for preparation of the phosphocalcic cement composition is also disclosed.

Phosphocalcic cement composition comprising blood

A method for promoting spine fusion inside intersomatic cages, comprising placing a fusion cage between two vertebral bodies, and injecting a bone cement paste inside said fusion cage, said bone cement paste containing a powder component comprising &#x3b1;-tricalcium phosphate (&#x3b1;-TCP) particles having an average size greater than or equal to 9 &#x3bc;m, and a liquid component comprising blood.

The present invention relates to a galliated calcium-phosphate biomaterial comprising a gallium-doped phosphocalcic compound of formula (I):CaGa(PO)&#x2003;&#x2003;(I)wherein 0&#x3c;x&#x3c;1 and the salts, hydrates and mixtures thereof and/or a calcium deficient apatite structure with in particular a (Ca+Ga)/P molar ratio in the range of 1.3 to 1.67, and a gallium content up to 4.5% by weight. It also relates to processes of preparation of such materials and uses thereof, in particular as dental or bony implants. It further relates to a kit comprising a galliated calcium-phosphate biomaterial in combination with a fluid component. It finally relates to methods of use of the galliated calcium-phosphate biomaterial, notably for III) ions increase radio-opacity after bone implantation and can be released for inhibiting bone resorption.

Galliated calcium phosphate biomaterials

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Le Loroux Bottereau, France

Charlotte Mellier