Starpharma Pty Limited

Charlotte Claire Williams

Brian Devlin Kelly

Guy Yeoman Krippner

Pasquale Razzino

Scott Andrew Henderson

Gottfried Lichti

Benjamin James Boyd

Phillip Martin Rendle

Lisa Michelle Kaminskas

Christopher John Hamilton Porter

Susanne Pallich

Angela Michelle Scheppokat

Ben William Greatrex

Zemin Wu

Christopher John Porter

The following invention is directed to macromolecules having controlled stoichiometry and topology, processes for their production, and applications for their use. The macromolecules have a controlled functional moiety stoichiometry and include at least one dendritic motif having a surface layer formed from at least one surface building unit and at least one subsurface layer formed from at least one building unit, the surface building unit and building units having a hydrocarbon backbone bearing a carbonyl group and at least one amine group; and at least two different functional moieties on the building unit and/or surface building unit; where functional moiety stoichiometry refers to the number and type of functional moieties.

Macromolecular compounds having controlled stoichiometry

The present invention relates generally to branched macromolecules bearing functional moieties. In particular, the invention relates to dendrimers, derived from lysine or lysine analogues, bearing a plurality of functional moieties. The invention further relates to the use of such macromolecules, particularly in therapeutic applications, and compositions comprising them.

Targeted polylysine dendrimer therapeutic agent

Growing community of inventors

Carlton, Australia

Charlotte Claire Williams