King Abdullah University of Science and Technology

Charlotte A E Hauser

Manuel Aranda Lastra

Carlos M Duarte

Sebastian Schmidt-Roach

Hepi Hari Susapto

Panagiotis Bilalis

Salwa Alshehri

Manola Moretti

Dana Alhattab

Sakandar Rauf

Rosario Perez Pedroza

Maria Hountondji

Abdulelah Alrashoudi

Alexander Valle Perez

Kowther Kahin

Sandip Jadhav

Zainab Khan

Hamed Albalawi

Hattan Boshah

Ali Aldoukhi

The present disclosure relates to Dopa containing ultrashort peptides capable of forming a gel, to a gel comprising a peptide in accordance with the present disclosure, and to a glue comprising a peptide in accordance with the present disclosure. Such gel is adhesive and is biocompatible. The peptides are suitable for building 3D structures, 3D printing, gluing as well as other applications.

Peptide-based Dopa containing adhesive gels

The present disclosure relates generally to an osteo-tissue graft capable of promoting bone tissue growth and regeneration, comprising at least one self-assemble peptide and mesenchymal stem cells (MSCs) in accordance with the present invention and a method of preparing such an osteo-tissue graft. The grafts are suitable for treatment of bone disorder or damages through tissue engineering, cellular replacement therapies as well as other applications.

Scaffolds from self-assembling tetrapeptides support 3D spreading, osteogenic differentiation and angiogenesis of mesenchymal stem cells

The present disclosure relates a method of fabricating a literal flow immunoassay (LFIA) for the diagnosis of diseases, including COVID-19. The present disclosure further relates to a fusion-epitopes peptide that can be used in the LFIA test to improve sensitivity, specificity and accuracy of the test.

Developing lateral flow immunochromatography (LFIA) peptide-based test strips for rapid detection of antigens and antibodies against specific antigens

Threaded coral reef nut

Coral farm crate

The present invention relates to a device and a method for building a 3D object by mixing a bioink solution, a buffer solution capable of inducing gelation of the bioink solution and a dispersion containing micro and/or nanoparticles, and ejecting the formed hydrogel out of a nozzle. The present invention further relates to a method of obtaining a hydrogel.

Device and method for microfluidics-based 3D bioprinting

The present disclosure relates to a coaxial nozzle for building a 3D tissue model. Accordingly, a nozzle for 3D tissue bioprinting may include at least one buffer solution inlet, at least one peptide inlet, at least one cell inlet, and a mixing chamber. The least one buffer solution inlet is attached to the at least one peptide inlet. The at least one cell inlet is attached to the at least one peptide inlet. The at least one buffer solution inlet may be attached from a side of the at least one peptide inlet, and the at least one cell inlet may be disposed externally and attached at an angle to the at least one peptide inlet.

Nozzle for 3D bioprinting

The present invention relates to peptides capable of forming a gel and to their use in tissue engineering and bioprinting. The present invention furthermore relates to a gel comprising a peptide in accordance with the present invention, to a method of preparing such gel and to the use of such gel. In one embodiment, such gel is a hydrogel. The present invention furthermore relates to a wound dressing or wound healing agent comprising a gel according to the present invention and to a surgical implant or stent comprising a peptide scaffold formed by a gel according to the present invention. Moreover, the present invention also relates to a pharmaceutical and/or cosmetic composition, to a biomedical device or an electronic device comprising the peptide according to the present invention.

Peptide capable of forming a gel for use in tissue engineering and bioprinting

Growing community of inventors

Thuwal, Saudi Arabia

Charlotte A E Hauser