Johns Hopkins University

Charles W Anderson

Harvey Wayne Ko

Micah A Carlson

Wayne A Bryden

Terry E Phillips

Scott A Ecelberger

Allan B Fraser

Richard C Benson

David R Kohler

C Brent Bargeron

Paul T Strickland

Daniel J DeCicco

John D Groopman

Michael P McLoughlin

Timothy J Cornish

Charles W Kerechanin, Ii

Peter F Scholl

William R Allmon

George L Vojtech

James T Velky

Nicholas H Evancich

William F Czages

Ronald G Chappell

A method of setting an apparent optical length of an optical fiber for a given optical wavelength includes heating the trimmed optical fiber to selectively vary a refractive index thereof in response to comparison of a determined arrival phase angle with a reference value representing a desired arrival phase angle to change the determined arrival phase angle so that a difference between the desired and determined arrival phase angles does not exceed an acceptable tolerance of a phase error.

Method of and apparatus for setting apparent length of optical fiber

A hand held, self-contained, automatic, low power and rapid sensor platform for detecting and quantifying a plurality of analytes. A sample solution potentially containing an unknown amount of an analyte is passed through an affinity column which contains antibodies to which the analyte binds thereby extracting the analyte. The affinity column is then rinsed to remove any other chemicals that may fluoresce. The rinsed affinity column is then eluted with a known volume of elution fluid causing the analyte to release from the antibody and dissolve in the fluid (eluant). The eluant is then placed in the quartz cuvette of a fluorometer. The analyte suspended in the eluant fluoresces at a waveband which is different than that of the light source that excites it. The amount of fluorescence is measured and the level of analyte determined. The rinsing and elution fluids, and/or the affinity column can be placed in a module for easy insertion and removal from the sensor when depleted or when the sensor is to be used against a different analyte.

Miniature immuno-optical rapid analyte sensor platform

An improved method for adhering a solid polymer component to a substrate is provided. An intermediate polymer adhesion promoting coating of metal oxide is applied to the substrate which enhances the adhesion of the subsequently applied solid polymer component to the substrate.

Method of adhering a solid polymer to a substrate and resulting article

A field portable mass spectrometer system comprising a sample collector and a sample transporter. The sample transporter interfaces with the sample collector to receive sample deposits thereon. The system further comprises a time of flight (TOF) mass spectrometer. The time of flight mass spectrometer has a sealable opening that receives the sample transported via the sample transporter in an extraction region of the mass spectrometer. The system further comprises a control unit that processes a time series output by the mass spectrometer for a received sample and identifies one or more agents contained in the sample.

Portable time-of-flight mass spectrometer system

Sample collection preparation methods for time-of flight miniature mass spectrometer

An expandable sensor array including at least one expandable member movable between an unexpanded stowed state and an expanded deployed state and a plurality of sensors interconnected with the at least one inflatable member and operatively connected to form a sensor array.

Expandable sensor array

Growing community of inventors

Woodbine, MD, United States of America

Charles W Anderson