Siemens Medical Solutions Usa, Inc.

Charles Russell Buchanan

James J Hamill

Stefan B Siegel

Andrew C Williamson

Mohammadreza Teimoorisichani

A method for generating transmission information in a time-of-flight positron emission tomography (PET) scanner having a patient tunnel and a plurality of PET detector rings. The PET scanner uses continuous bed motion to move a patient bed and patient through the patient tunnel. The patient receives a positron-emitting radioisotope dose prior to undergoing a PET scan. The method includes storing a positron-emitting radioisotope in a radiation shielded container. The method also includes moving the radioisotope into a stationary vessel located adjacent to the PET detectors and within a field of view of the PET scanner at substantially the same time that the patient receives the radioisotope dose to form a stationary transmission source wherein transmission information is generated while the bed undergoes continuous bed motion. Further, the method includes withdrawing the radioisotope from the vessel when the PET scan is complete and storing the radioisotope in the container.

PET transmission source based on continuous bed motion

An apparatus for manufacturing a radioisotope comprises a container. The container comprising a portable neutron source and a solution that comprises a particular isotope. The portable neutron source is surrounded by the solution. The solution comprises at least one of copper phthalocyanine or copper salicylaldehyde o-phenylene diamine. The portable neutron source emits neutrons that react with the particular isotope resulting in the transformation of the particular isotope into the radioisotope.

Compact radioisotope generator

Disclosed are a method and apparatus for making a radioisotope and a composition of matter including the radioisotope. The radioisotope is made by exposing a material to neutrons from a portable neutron source.

Composition of matter comprising a radioisotope composition

A method and apparatus for making a radioisotope and a composition of matter including the radioisotope. The radioisotope is made by exposing a material to neutrons from a portable neutron source. More specifically, a solution includes a particular isotope. The neutron source is completely surrounded by the solution. The solution is exposed to the neutrons. Generated radioisotopes are extracted from the solution.

A method and device for reducing positron emitter isotope labeled COto positron emitter isotope labeled CO generally includes introducing a volume of positron emitter isotope labeled COinto a first heated reaction vessel comprising a metal oxide, such as Iron (II) Oxide such that the COis reduced to CO upon contact with the Iron (II) Oxide. The volume is then transferred to a second reaction vessel to remove any un-reacted CO, preferably, via a soda-lime trap. The volume is then transferred to a target, e.g., a storage vessel or subject. The COincludes one of [C] or [O]. The first reaction vessel is, preferably, heated to a temperature of between 900 and 1000&#xb0; C., and more preferably, to between 925 and 975&#xb0; C., and even more preferably, to approximately 950&#xb0; C. Preferably, the Iron (II) Oxide powdered and has a particle size of about &#x2212;10 mesh.

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Knoxville, TN, United States of America

Charles Russell Buchanan