Acelrx Pharmaceuticals, Inc.

Vertical Pharmaceuticals, Inc.

Koninklijke Philips Corporation N.v.

Aceirx Pharmaceuticals, Inc.

Charles Rampersaud

Andrew I Poutiatine

Bruce P Edwards

Pamela Palmer

Thomas A Schreck

Stelios Tzannis

William Kolosi

Sascha Retailleau

Edmond Chiu

Benjamin K Yaffe

Larry Hamel

Bradley Blackwood

Lawrence Hamel

Ryan Boucher

Craig A Purdy

Edward M Gillis

Scott Anthony McGill

Joe Paraschac

Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.

Storage and dispensing devices for administration of oral transmucosal dosage forms

Systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject using a device are disclosed. The dispensing device includes a lock-out feature and a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.

Apparatus for administering small volume oral transmucosal dosage forms

Methods and apparatus for administering small volume oral transmucosal dosage forms

Methods for administering small volume oral transmucosal dosage forms using a dispensing device

Drug storage and dispensing devices for dispensing dosage forms to the oral mucosa of a patient are disclosed. The drug storage and dispensing device is a single dose applicator or a device which includes a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.

Drug storage and dispensing devices for dispensing a drug dosage form to a patient are disclosed. A cartridge includes a cartridge housing and a pusher. The cartridge housing defines a channel within which multiple tablets are disposed. The cartridge housing is configured to be removably coupled to a tablet dispensing device. A first portion of the pusher is disposed outside of the channel. A second portion of the pusher is movably disposed within the channel, and is configured to exert a force on the plurality of tablets to convey a first tablet from the channel into the tablet delivery device when the force is exerted on the first portion of the pusher.

Drug storage and dispensing devices and systems comprising the same

Compositions, systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject for treatment of pain using a device are disclosed.

Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain

Compositions, methods and systems for administration of small volume sufentanil-containing drug dosage forms to the oral mucosa of a subject are disclosed.

A method of administering small, bioadhesive drug tablets includes moving an end portion of a delivery member. A surface of the delivery member can be positioned to prevent movement of the drug tablet from a tablet cartridge channel to a delivery passage of a delivery device when the end portion of the delivery member is in a first stopped position. The end portion of the delivery member can be moved to a second position within the delivery passage such that the tablet cartridge channel is in communication with the delivery passage. The drug tablet can be conveyed into the delivery passage via the tablet cartridge channel. The end portion of the delivery member can be moved to a third position within the delivery passage to convey the drug tablet through an exit opening of the delivery device.

Method of moving a delivery member of a dispensing device for administration of oral transmucosal dosage forms

Drug storage and dispensing devices for dispensing a drug dosage form are disclosed. Devices having a housing defining a nonlinear passageway and a flexible push rod to move within the nonlinear passageway are disclosed. Devices having a flexible push rod coupled to a rotation actuating member at at an end portion thereof are also disclosed.

Growing community of inventors

San Francisco, CA, United States of America

Charles Rampersaud