Bracco Diagnostics Inc.

Bracco Research, USA

Brocco Diagnostics, Inc.

Charles R Quirico

Ernest Balestracci

Jacob S Childs

Daniel Darst

Irene K Ropiak

Eric Jason Krause

Vishal N Lokhande

John J Niedospial, Jr

Julius P Zodda

Daniel V Clements

Peter B Madson

Ernst Schramm

Jo Anna Monteferrante

James A Melchore, Jr

Rolf E Swenson

Janet L Gelbach

Fred E Snyder

Michael N Eakins

Lawrence Callan

Rebecca V Fisher

Irene Kucharewicz Ropiak

Daniel D Darst

Infusion system configurations and assemblies facilitate routing of infusion circuit tubing lines. Tubing lines are routed into and out from compartments of a shielding assembly for the infusion system, at locations which prevent kinking and/or crushing of the lines, and/or provide for ease in assembling the circuit. A plurality of the lines may be held together by a support frame to form a disposable infusion circuit subassembly, that can further facilitate routing of the lines.

Infusion system configurations

A shielding assembly for an infusion system includes a plurality of compartments and a door for each compartment, and provides a radioactive radiation barrier for the compartments. One of the compartments contains a radioisotope generator of the infusion system and another of the compartments may contain a waste bottle of the infusion system. An opening into each of the generator and waste bottle compartments may be oriented upward, and the opening into the latter may be at a higher elevation than the opening into the former, for example, to facilitate independent removal and replacement of each. A door of at least one of the compartments, other than the generator compartment, when closed, may prevent the door of the generator compartment from being opened. A cabinet structure for the infusion system may enclose the shielding assembly and secure the generator.

Shielding assemblies for infusion systems

A cabinet structure for an infusion system includes a platform, on which the system is mounted, and a shell surrounding an interior space, which contains at least a portion of the system. The shell preferably includes an opening that is sized and oriented to allow a lowering of a radioisotope generator, for the system, into the interior space, and a lifting of the generator out from the interior space. The shell may further include another opening, located at a higher elevation than the aforementioned opening, in order to provide access to a waste bottle of the infusion system.

Cabinet structure configurations for infusion systems

A radioisotope generator system can include a column assembly having a column, an inlet arm, an outlet arm. The column can contain packing material that binds a radioisotope. In addition, the column may define a notch between an open area and a stopper receptacle area in which an opening of the outlet arm is positioned. In some examples, the system includes a Luer lock connection between the outlet arm and a connector tubing. The Luer lock connection can include a male Luer cap and a female Luer cap each comprising tabs configured to line up with or overlap each other so as to indicate when the caps are sufficiently tightened together so as to form a non-leaking lock.

Containers for pharmaceuticals, particularly for use in radioisotope generators

Shielding assemblies for systems that generate and infuse radiopharmaceuticals. The shielding assemblies include a sidewall that defines several compartments and provides a radiation barrier for the compartments and provides a passageway sized to accommodate routing of an eluate line from a radioisotope generator. One compartment is sized to contain the radioisotope generator. A second compartment is sized to hold a portion of an infusion circuit that may be an extension of the eluate line and may include a waste line and a patient line.

Infusion systems configurations

The invention is directed to improved containers for pharmaceuticals and any tubing and tubing connectors associated therewith, particularly containers for pharmaceuticals which are irradiated, heated or otherwise subjected to increased pressure. In a preferred embodiment, the invention is directed to an improved container for use in a radioisotope generator, such as a rubidium-82 generator.

Infusion circuit subassemblies

Twist valve for a medical bag

A twist valve for use in a fluid delivery system is provided for selectively allowing fluid flow and blocking fluid flow therethrough. The twist valve is in communication with a pre-filled flexible container and includes a proximal part and a distal part each having a fluid inlet and a fluid outlet. The proximal and distal parts are equipped with cylindrical helical surfaces which allow them to move toward or away from each other when a twisting force is applied to them. The fluid outlet of the proximal part is blocked with a stopper in the distal part when the twist valve is in the closed position, and is unblocked by the stopper when the twist valve is in the open position.

Twist valve

Collapsible, non-vented medical container for the containment and delivery of parenteral solutions, the container having

Collapsible medical bag for the containment and delivery of diagnostic

Flexible medical fluid container

Growing community of inventors

Warren, NJ, United States of America

Charles R Quirico