Adir Et Compagnie

Boehringer Ingelheim Gmbh

Riom Laboratories - Cerm S.a.

Laboratories Negma

Charles Lespagnol

Daniel Lesieur

Said Yous

Jacqueline Bonnet

Beatrice Guardiola

Daniel H Caignard

Isabelle Lesieur

Michelle Devissaguet

Norbert Busch

Henri Baille-Barrelle

Maurice Vigneron

Jean-Claude Fruchart

Hocine Aichaioui

Nicole Monfilliette

Jacques Sauzieres

Ziaddine Moussavi

Compounds of general formula (I): ##STR1## in which: R.sub.1 represents a hydrogen atom or a lower alkyl group,

Benzothiazolinone compounds

Compounds of general formula (I): ##STR1## in which: R.sub.1 denotes a hydrogen atom or a lower alkyl optionally substituted with a hydroxyl group,

Analgesic benzoxazolinones having at the 6-position a

Compounds of general formula(I): ##STR1## in which: R.sub.1 represents a hydrogen atom or a lower alkyl group,

Compounds of general formula (I): ##STR1## in which: R.sub.1 represents a hydrogen atom or a lower alkyl group, A represents a hydrogen atom, and in this case B represents a group CO-G, G being:

Acylbenzoxazolinones compounds

Benzoxazolinone compounds, compositions and use

The invention relates to products characterized by the general formula: ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R and X have the meanings indicated in claim 1. The invention also related to pharmaceutical compositions administrable particularly orally, containing the abovesaid compounds in association with a pharmaceutically acceptable vehicle. They are useful as medicaments.

Use of 7-acyl benzoxazinones and their derivatives in treating

The invention relates to compounds of the formula: ##STR1## in which R represents hydrogen or a lower alkyl radical and R.sub.1 and R.sub.2 separately represent hydrogen, a lower alkyl, cycloalkyl or benzyl radical, or represent, together with the nitrogen atom to which they are bonded, a heterocyclic radical such as a morpholino, 4-(pyrimidin-2-yl)-piperazinyl or 4-phenylpiperazinyl the phenyl radical of which being optionally substituted by halogen, lower alkoxy or trifluoromethyl, having CNS activity and particularly hypnotic properties. Moreover the compounds in which R.sub.1 and R.sub.2 are hydrogen can be used in the treatment of heart failure.

Benzoxazolinones

Compounds of the formula ##STR1## wherein X and Y, which may be identical to or different from each other, are each hydrogen or halogen,

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Lambersart, France

Charles Lespagnol