Maquet Cardiovascular LLC

Ancora Heart, Inc.

Origin Medsystems, Inc.

Charles J Adam

John P Lunsford

John W Davis

Joseph N Lamberti

Albert K Chin

Russel Mahlon Sampson

Michael C Stewart

Geoffrey H Willis

Son Truong Nguyen

Arthur M Lin

Kenny L Dang

David Scott Baron

David E Hancock

Justin Williams

Harry Ino

Jennifer Henderson

Jeff Closs

Joshua Sampson

Ryan Charles Abbott

Mariel Fabro

Brian Tang

Liming Lau

Eugene Serina

Tammy Y Tam

Peter L Callas

Tenny C Calhoun

Stephen Olson

Stephen Clark Meier

Kimberly D Barkman

Ravinder D Pamnani

Stephen C (deceased) Meier

Russel Sampson

Son Nguyen

The devices and methods described herein may be used to restore left ventricular function to address mitral valve regurgitation. One variation of an implant comprises a plurality of tethered anchors and a plurality of force-distribution members slidably disposed on the tether between the anchors. One or more of the force-distribution members can comprise a bioabsorbable material. Methods comprise deploying the implant to cardiac tissue, cinching the implant to its hard stop (e.g., where further cinching does not cause further tissue tightening), providing a pre-selected amount of slack to the implant after it has been cinched to its hard stop configuration, and securing a lock member on the tether. Also disclosed herein are lock member deployment catheters that provide a pre-selected amount of tether slack as it secures a lock member on the tether.

Myocardial implant load sharing device and methods to promote LV function

Disclosed herein are devices and methods for assessing the surface of a target cardiac tissue and for delivering a tissue anchor to cardiac tissue at a preselected depth within the myocardium in a beating heart procedure. In one variation, an anchor delivery device comprises an elongate body, a tissue anchor disposed within a first longitudinal lumen of the elongate body, and a tissue depth indicator slidable within a second longitudinal lumen of the elongate body. The tissue depth indicator has a first configuration that indicates the boundary of the surface of the target tissue and a second configuration that indicates when the distal tip of the elongate body has been advanced to a preselected depth into the target tissue. In some variations, a tissue depth indicator may also be configured to resist or limit the penetration of the delivery device into tissue after a preselected depth has been reached.

Devices and methods of visualizing and determining depth of penetration in cardiac tissue

Components for an endoscopic vessel harvesting system suitable for harvesting target vessels such as the saphenous vein or radial artery for cardiac artery bypass graft surgery. The main components of such systems include a vessel dissector and a vessel harvester, both of which work in conjunction with a separately provided endoscope. The vessel dissector is an elongated cannula having a blunt tip for separating layers of facial around vessels. The tip may be movable, and is typically transparent to permit viewing forward of the tip using the endoscope. Internal features of the tip may reduce glare back to the endoscope. Several devices improve visibility through the tip by reducing interference from tissue or fluid on the tip. The vessel harvester also has an elongated cannula for receiving the endoscope. Several tools within the harvester permit manipulation, severing, and sealing of vessels forward of the distal end. The tool for manipulating vessels may have a low-profile for increased visibility of operation, and may be coupled to the cannula with a damping mechanism to reduce the possibility of avulsion of the vessels. Various vessel cutting and sealing devices are provided that may accommodate various sizes of vessels and improve cutting and sealing efficacy.

Endoscopic vessel harvesting system components

Devices and methods for locking and/or cutting tethers during a tissue modification procedure are described. In some variations, a tether may be used to tighten tissue by bringing two pieces or sections of the tissue together. The tether, which may be under tension, may be locked to maintain the tension, and excess tether may be severed, using one or more of the devices and/or methods. The devices and/or methods may be used, for example, in minimally invasive procedures.

Termination devices and related methods

A vessel harvesting system that is suitable for harvesting target vessels such as the saphenous vein or radial artery for cardiac artery bypass graft surgery. The system includes a vessel harvesting tool with an elongated cannula and a plurality of surgical instruments therein for separating the target vessels from the surrounding tissue and side branches. The harvesting tool includes a modular handle unit with a base attached to the elongated cannula and a sled that can adapt the base to various types of vessel severing/securing tools, such as tissue welders, bipolar scissors, and bipolar bisectors. The handle unit may be relatively rigid and integrated with the various tool movement controls to facilitate one-handed operation by a user. A severing/securing tool rotation mechanism may be incorporated within the handle and operated by a thumbwheel or other such mechanism. The vessel harvesting system may also provide distal COinsufflation for enhanced maintenance of the operating cavity.

Modular vessel harvesting system and method

A surgical apparatus includes an elongate cannula having a lumen extending therein between proximal and distal ends, a retractor disposed to slide within the lumen to extend a distal end thereof beyond the distal end of the cannula, an angling device connected to the retractor near the distal end of the retractor and extending within the cannula toward the proximal end thereof for selectively deflecting the distal end of the retractor away from a central axis of the cannula in response to manual manipulation of the angling device from near the proximal end of the cannula, wherein the distal end of the retractor is configured to move, upon extension, an object away from the central axis of the cannula.

Vessel retractor

Surgical treatment of tissue includes electro cauterization of blood vessels interposed between spaced sets of electrodes of opposite polarity, and includes transection of such tissue by a cutter that is mounted between the spaced sets of electrodes for translational and lateral movement relative to the sets of electrodes. Orientations of the sets of electrodes within a range of angles about an elongated axis of a supporting body are controlled by manual movement of an actuator mounted near a proximal end of the body for movement through a smaller range of angles via linkage connecting the actuator to the electrodes. Tissue dissection with gas insufflation to form an anatomical space in tissue is facilitated by a fluid outlet port located near the tissue-dissecting tip at the distal end of the elongated body that delivers through the tissue-dissecting tip to the dissected tissue a fluid under pressure that is supplied along a lumen within the elongated body.

Apparatus and method for integrated vessel ligator and transector

Surgical treatment of tissue includes electrocauterization of blood vessels interposed between spaced sets of electrodes of opposite polarity, and includes transection of such tissue by a cutter that is mounted between the spaced sets of electrodes for translational and lateral movement relative to the sets of electrodes. Orientations of the sets of electrodes within a range of angles about an elongated axis of a supporting body are controlled by manual movement of an actuator mounted near a proximal end of the body for movement through a smaller range of angles via linkage connecting the actuator to the electrodes. Tissue dissection with gas insufflation to form an anatomical space in tissue is facilitated by a fluid outlet port located near the tissue-dissecting tip at the distal end of the elongated body that delivers through the tissue-dissecting tip to the dissected tissue a fluid under pressure that is supplied along a lumen within the elongated body.

Integrated vessel ligator and transector

A tissue dissector and method for welding and severing blood vessels includes advancing the tip of a tissue-dissecting surgical instrument through tissue, with a tissue welder substantially concealed within the tip during tissue dissection. Blood vessels encountered in the tissue being dissected are selectively captivated and compressed in substantial contact with the tissue welder to elevate the temperature of the compressed tissue sufficiently to hemostatically weld and sever the compressed blood vessel.

Dissection and welding of tissue

A retractor and a surgical tool are positioned within a cannula, and a dissection cradle of the retractor is positioned at the distal end of the cannula. The retractor includes a first portion with an axis approximately parallel to the axis of the cannula and a second portion with an axis that can be skewed relative to the axis of the cannula. The dissection cradle is located at the distal end of the second portion of the retractor, and may include two substantially parallel, spaced legs with the retractor shaped in a loop between and in a plane skewed relative to the axes of the legs, and with the loop directed away from the surgical tool. Thus, in operation, a surgeon locates a vessel and side branch of interest and extends the retractor to cradle the vessel in the dissection cradle. Once cradled, the retractor may be deflected to urge the vessel away from the axis of the cannula to isolate the side branch for exposure to the surgical tool. Removable, transparent tips are selectively positioned at the distal end of the cannula for performing dissection and transection via a single cannula. Additionally, the tips are configured to align the apices of the tips with the central axis of the endoscope to maximize the visual field through the tips via the endoscope. Wing-like protrusions on an alternate tip for the cannula facilitate tissue dissection in forming a tunnel in tissue along a target vessel. Swept back forward edges on the wing-like protrusions promote easy tissue dissection using reduced force to advance the cannula and alternate tip through tissue surrounding the target vessel.

Vessel retraction device and method

A retractor and a surgical tool are positioned within a cannula, and a dissection cradle of the retractor is positioned at the distal end of the cannula. The retractor includes a first portion with an axis approximately parallel to the axis of the cannula and a second portion with an axis skewed relative to the axis of the cannula. The dissection cradle is located at the distal end of the second portion of the retractor, and may include two substantially parallel, spaced legs with the retractor shaped in a loop between and in a plane skewed relative to the axes of the legs, and with the loop directed away from the surgical tool. Thus, in operation, when the surgeon locates a vessel and side branch of interest, the surgeon extends the retractor to cradle the vessel in the dissection cradle. Once cradled, the retractor may be fully extended to urge the vessel away from the axis of the cannula to isolate the side branch for exposure to the surgical tool. Removable, transparent tips are selectively positioned at the distal end of the cannula for performing dissection and transection via a single cannula. Additionally, the tips are configured to align the apices of the tips with the central axis of the endoscope to maximize the visual field through the tips via the endoscope. Wing-like protrusions on an alternate tip for the cannula facilitate tissue dissection in forming a tunnel in tissue along a target vessel. Swept back forward edges on the wing-like protrusions promote easy tissue dissection using reduced force to advance the cannula and alternate tip through tissue surrounding the target vessel.

Combined vessel dissection and transection device and method

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San Jose, CA, United States of America

Charles J Adam