Novartis Ag

Alcon, Inc.

Alcon Manufacturing, Ltd.

Alcon Universal Ltd.

Alcon Laboratories, Inc.

Omya International Ag

Charles Freeman

Mutlu Karakelle

Walter R Laredo

Albert R Leboeuf

Chance Lehman

Douglas C Schlueter

Joseph I Weinschenk, Iii

Robert A Scott

Michael John Simpson

David Jinkerson

Ali E Akinay

Thomas A Callaghan

Joseph McJunkins

David L Jinkerson

Joseph D Menczel

Joseph Mcjunkins

Joseph I Weinschenk

Iii Joseph I Weinschenk

A coating composition comprising an aqueous dispersion of submicron natural ground calcium carbonate particles contained in a liquid binder, wherein the resultant coating may constitute either a clear coat or a glossing and opacifying coating, depending upon the presence of certain additives such as a mineral pigment (e.g., TiO). The composition is characterised in that comprises, in the case of a clear coating, at least one ground natural calcium carbonate having a median diameter of between 0.05 and 0.15 &#x3bc;m, while in the case of a glossing and opacifying coating, at least one ground natural calcium carbonate having a median diameter of between 0.05 and 0.3 &#x3bc;m and at least one pigment having a refractive index of greater than or equal to 2.5.

Coating composition comprising submicron calcium carbonate-comprising particles, process to prepare same and use of submicron calcium carbonate-comprising particles in coating compositions

High refractive index copolymers with reduced glistenings are disclosed. The copolymers, which are particularly suitable for use as ophthalmic device materials, comprise a high molecular weight, reactive, linear polyethylene glycol component.

High refractive index, acrylic ophthalmic device materials with reduced glistenings

High refractive index copolymers with reduced tack are disclosed. The copolymers, which are particularly suitable for use as ophthalmic device materials, comprise a benzhydryl methacrylate or benzhydryl methacrylate derivative monomer.

High refractive index ophthalmic device materials with reduced tack

Ophthalmic device materials comprising 2-amino benzophenone UV-absorbing compounds are disclosed. The ophthalmic device materials are particularly useful in intraocular lenses.

2-amino benzophenone UV-absorbers for ophthalmic lens materials

An exemplary embodiment provides a biocompatible polymer composition suitable for making intraocular lenses, especially posterior chamber phakic lenses, that includes a hydrogel having an equilibrium water content of less than about 55 wt. %. The hydrogel has a refractive index greater than about 1.41 and a sodium ion flux between about 16 to about 20 &#x3bc;eq-mm/hr/cm.

High ion and metabolite flux lenses and materials

High refractive index copolymers suitable for use in ophthalmic devices are disclosed. The copolymers comprise two or more aryl hydrophobic monomers and a non-polymerizable propylene oxide-ethylene oxide-propylene oxide block copolymer surfactant having a molecular weight of approximately 3600 and approximately 40% ethylene oxide units by weight. The copolymers have a reduced tendency to form glistenings when stored in water at physiological temperatures compared to similar copolymers lacking the non-polymerizable surfactant.

High refractive index ophthalmic device materials

High refractive index copolymers suitable for use in ophthalmic devices are disclosed. The copolymers comprise a single aryl hydrophobic monomer as a device forming monomer. In addition, the copolymers comprise a non-polymerizable block copolymer surfactant. The copolymers have a reduced tendency to form glistenings when stored in water at physiological temperatures.

Foldable intraocular lenses having a reduced risk of posterior capsule opacification are disclosed. The foldable intraocular lenses have optics that are prepared such that their surface is glassy and their bulk is rubbery.

Foldable intraocular lens optics having a glassy surface

Disclosed are soft, high refractive index, acrylic materials having an elongation of at least 150%. These materials, especially useful as intraocular lens materials, contain an aryl acrylic hydrophobic monomer as the single principal device-forming monomer. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.

Foldable ophthalmic and otorhinolaryngological device materials

A method of selecting an intraocular lens material for toric lenses is disclosed. The method comprises determining the tack of the material.

Toric intraocular lens material

A method of selecting an intraocular lens material for reducing the risk of posterior capsule opacification is disclosed. The method comprises determining the tack of the material.

Method of selecting an intraocular lens material

Improved soft, foldable acrylic lens materials which are particularly suited for use as IOLs, but which are also useful as other ophthalmic devices, such as contact lenses, keratoprostheses, and corneal rings or inlays, are disclosed. These materials contain only two principal components: one aryl acrylic hydrophobic monomer and one hydrophilic monomer. The materials of the present invention are copolymers comprising at least about 90% by weight of the two principal monomeric components; provided that the amount of the hydrophilic component is not greater than that of the aryl acrylic hydrophobic component. The remainder of the material comprises up to 10% by weight of one or more additional components, such as cross-linking, UV-light absorbing, and blue-light absorbing components. The aryl acrylic hydrophobic monomers suitable for use in the materials of the present invention have the formula ##STR1## wherein: X is H or CH.sub.3 ;

Growing community of inventors

Granbury, TX, United States of America

Charles Freeman