Adir Et Compagnie

Science Union Et Cie

Science Union Et Cie, Societe Francaise De Recherche Medicale

Science Union Et Cie, Societe Francaise De Recherche Medical

Adir

Adir, S.a.r.l.

Science Union Et Cie, Societe Francaise De Recherche Med.

Charles E Malen

Michel Laubie

Pierre Roger

Jean-Claude Poignant

Guillaume De Nanteuil

Xavier B Pascaud

Jean-Michel Lacoste

Francis Colpaert

Monique Desnos

Jacques Duhault

Jean-Paul Vilaine

Pierre Hugon

Laszlo Beregi

Jean C Poignant

Albert Lenaers

Jean-Louis Peglion

Pierre Desnoyers

A compound of formula (I): ##STR1## in which: R.sub.1 represents substituted or unsubstituted phenyl or (C.sub.3 -C.sub.7) cycloalkyl,

Guanidine compounds

The invention relates to the compounds of formula (I): ##STR1## in which R represents higher alkyl, 1-(higher alkyl)lower cycloalkyl-1-yl or higher alkenyl comprising one or more double bonds, and either

Acylaminophenol compounds

The invention relates to compounds of general formula (I). ##STR1## in which X represents an atom of sulfur or oxygen, or a substituted or unsubstituted amino group; R represents a hydrogen atom or any one of groups A, B, C, D, E, F or G; R' represents a hydrogen atom, an alkyl group or any one of groups A, B, C, D, E or F, with R'=H when R=G; or R and R' form, with the nitrogen atom to which they are attached, an optionally substituted piperazine ring.

Aminomethylpiperidine compounds

The invention relates to compounds of general formula (I). ##STR1## in which X represents an atom of sulfur or oxygen, or a substituted or unsubstituted amino group;

New aminomethylpiperidine compounds

A compound selected from those of formula (I): ##STR1## in which R represents straight-chain or branched lower (C.sub.1 -C.sub.6) alkyl, (C.sub.3 -C.sub.8) cycloalkyl, optionally substituted phenyl, pyridyl or naphthyl, and

Substituted trifluoropropan-1-yl-imidazole alpha 2-receptor anagonists

The invention relates to compounds of general formula: ##STR1## in which A, B, G, D which may be identical or different, each denote a hydrogen atom or a halogen atom, a lower alkoxy group or alternatively a lower alkyl group optionally substituted with one or more halogen atoms,

Novel tricyclic indole compound

The invention concerns 5-[(3-chloro-6-methyl-5,5-dioxo-6,11-dihydro-dibenzo (c,f) (1,2) thiazepin-11-yl)-amino] pentanoic acid. Medicament.

Tricyclic compound called

Compounds of the formula: ##STR1## in which: R.sub.1 and R.sub.2 each represent, independently of one another, hydrogen, halogen, alkyl or alkoxy having from 1 to 4 carbon atoms, sulphonamide possibly substituted by an alkyl radical having from 1 to 4 carbon atoms; or together methylenedioxy, n is 0 or 1,

Bicyclo (4.2.0) 1,3,5-octatriene compounds and use as .alpha.-adrenergics

Compounds corresponding to the general formula: ##STR1## in which X and Y identical or different, represent a hydrogen or a halogen atom, a lower alkyl, a lower alkoxy or a trifluormethyl group,

Tricyclic ethers, their preparation and the pharmaceutical compositions

This invention relates to novel tricyclic ethers, pharmaceutically acceptable addition salts and optical isomers therefrom. The compounds described herein are useful as psychotropic agents in the treatment of depression and anxiety. Also included herein are methods of preparing said compounds, pharmaceutical compositions including them and methods of treating human or animal beings by administering these pharmaceutical compositions.

Tricyclic ethers, their process of preparation and their use as medicines

This invention relates to trifluorethylamines and to a process for producing the same. These trifluorethylamines are substituted on the nitrogen atom with a lower alkyl or a cyclo lower alkyl radical. They are endowed with interesting pharmacological properties.

2-[Trifluoroethylamine]oxazolines

This invention relates to novel substituted aryl lower alkamine and more precisely to arylmethylamine, the methyl group of which is substituted with one more polyfluoromethyl radicals. This invention also relates to the process for producing said compounds. The resulting compounds have pharmacological utility and may be used as a drug in human and veterinary medicine.

Novel aryltrifluoroethylamines and processes for producing the same

Certain phenyl amines have been prepared wherein the 'methyl' carbon is substituted with a polyfluoroalkyl radical. The compounds form acid addition salts, exist in resolvable stereoisomeric forms, and are useful for treating hypertension. Formulations for human and veterinary medicine are described, as well as methods of use.

Growing community of inventors

Fresnes, France

Charles E Malen