Boston Scientific Scimed, Inc.

Biotronik Ag

Charles Deng

Torsten Scheuermann

Dennis A Boismier

Jacob Drew Edick

Jan Weber

Jonathan Swift Stinson

Louis Toth

Liliana Atanasoska

Steven R Larsen

Jan Webber

Pankaj Gupta

A bioerodible endoprosthesis includes a bioerodible magnesium alloy. The bioerodible magnesium alloy has magnesium and one or more additional alloying elements, including aluminum. The alloy has a microstructure comprising equiaxed Mg-rich solid solution phase grains having an average grain diameter of less than or equal to 5 microns and continuous or discontinuous second-phase precipitates in grain boundaries between the Mg-rich solid solution-phase grains, the second-phase precipitates having an average longest dimension of 0.5 micron or less.

Bioerodible magnesium alloy microstructures for endoprostheses

A bioerodible endoprosthesis includes a bioerodible magnesium alloy. The bioerodible magnesium alloy has a microstructure including equiaxed Mg-rich solid solution-phase grains having an average grain diameter of less than or equal to 5 microns and second-phase precipitates in grain boundaries between the equiaxed Mg-rich solid solution-phase grains. The beta-phase precipitates have an average longest dimension of 0.5 micron or less. The microstructure can be produced by one or more equal-channel high-strain processes.

An endoprosthesis includes an expandable tubular body defined by a plurality of struts. In some embodiments, the expandable tubular body includes a bioerodible metal that has at least a first surface region and a second surface region. The first and second surface regions can have different surface oxide compositions. In some embodiments, the first portion has a thermally altered microstructure and the second portion has a wrought microstructure. The thermally altered microstructure can be a cast microstructure comprising dendritic grains. The first portion forms at least a portion of an outer surface of the expandable tubular body. In some embodiments, the expandable tubular body includes iron or a bioerodible iron alloy and at least one surface of the expandable tubular body includes a substantially uniform coating of iron(III) oxide.

Surface treated bioerodible metal endoprostheses

A medical implant includes iridium oxide. The iridium oxide has a plurality of Ir&#x2014;O &#x3c3; bonds and a plurality of Ir&#x2550;O &#x3c0; bonds. The iridium oxide has a ratio of the Ir&#x2014;O &#x3c3; bonds to the Ir&#x2550;O &#x3c0; bonds that is greater than 1.3.

Medical implants including iridium oxide

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Chanhassen, MN, United States of America

Charles Deng