Luna Innovations Inc.

Charles D Pennington

Mark E Jones

Jennifer L Elster

Joshua P Averett

Roger L Van Tassell

A biosensor having enhanced sensitivity to physical or chemical parameters comprises a waveguide and a coating disposed on the waveguide. The coating has a refractive index that enhances the sensitivity of the biosensor to physical or chemical parameters. In a preferred embodiment, the coating comprises at least one dendrimer disposed on the waveguide, wherein the coating has a refractive index ranging from about 1.0 to about 1.5. A method for fabrication of the biosensor is also provided.

Biosensors having enhanced environmental sensitivity

The present invention is for a fiber optic flow cell. The flow cell comprises a substrate having at least one sample channel and at least one optical fiber channel holder. At least one optical fiber is disposed within each optical fiber channel holder. Each optical fiber has at least one grating wherein each grating is in contact with each sample channel, defining a sensing area. At least one sample port is positioned in an operable relationship to at least one sample channel. Alternatively, at least one sample outlet is positioned in an operable relationship to at least one sample channel. The flow cell may be of a modular design providing a flow cell kit that contains pieces that may be assembled to form custom-made flow cells. The flow cell is used for conducting measurement studies on a sample.

Fiber-optic flow cell and method relating thereto

A fiber-optic method for making simultaneous multiple parameter measurements employs an optical fiber sensor having at least one long period grating disposed therein. An excitation is created in the optical fiber sensor wherein a plurality of evanescent field sensing depths result. At least two long period grating signatures are created. When the optical fiber sensor is exposed to at least one material, changes in the material are identified by simultaneously measuring and comparing shifts in each long period grating signature; correlating the shifts to changes in the material; and solving a series of equations that compare changes in the coupling wavelength for a specific loss band. A reactive coating may be applied to the optical fiber sensor proximate to the long period grating such that changes in the reactive coating as it reacts with the material may also be monitored.

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Blacksburg, VA, United States of America

Charles D Pennington