Other

Hsc Research Development Corporation

Charles A Ward

Walter Zingg

A method for treating porous polytetrafluoroethylene and other types of synthetic materials having low surface tension to render the material suitable for use in bonding to living tissue. The synthetic material is enveloped with a liquid of sufficiently low surface tension to permit the liquid to enter the pores of the material. The liquid has a sufficiently low gas content to enable the liquid to absorb or displace essentially all gas nuclei held in the pores of the material as the liquid fills essentially all pores. After the low surface tension liquid has permeated all pores of the porous material, such liquid is replaced with a solution compatible with the body fluid and in which proteins have a low solubility to render the material suitable for implant. When such material is placed in contact with exposed tissue, an immediate bond is formed which permits implanting the material without the need of sutures to hold the material in place.

Preparation of synthetic materials for implantation in mammalian tissue

Method and apparatus are provided for treating one surface of a wall of articles to be used in contact with blood. A solution which is compatible with blood is brought into contact with the surface and a partial vacuum is applied to the wall for a predetermined time period. This partial vacuum causes gas nuclei trapped in irregularities in the surface to permeate through the wall. Consequently when blood displaces the solution there is less likelihood of blood platelets being trapped on the surface with eventual blood clotting.

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Toronto, Canada

Charles A Ward