Georgetown University

Charbel Moussa

Christian Wolf

Balaraman Kaluvu

Provided herein are compositions and methods for treating or preventing a neurodegenerative disease, a myodegenerative disease, a prion disease or a lysosomal storage disease in a subject.

Compositions and methods for treating neurodegenerative, myodegenerative, and lysosomal storage disorders

Provided herein are methods of treating a lysosomal storage disorder (LSD) in a subject and methods of promoting lysosomal clearance in one or more cells of a subject.

Compositions and methods for treating lysosomal storage disorders

Provided herein are methods of treating or preventing a neurodegenerative disease, a myodegenerative disease or a prion disease in a subject comprising administering a tyrosine kinase inhibitor.

Treating neural disease with tyrosine kinase inhibitors

Provided herein are methods of promoting parkin activity in a subject, comprising: selecting a subject with a disorder associated with decreased Parkin activity; and administering to the subject an effective amount of a composition that increases parkin activity, wherein the composition is an inhibitor of a deubiquitinating enzyme.

Growing community of inventors

Germantown, MD, United States of America

Charbel Moussa