The United States of America, As Represented by the Secretary, Department of Health and Human Services

Chao-Ming Tsai

Xin-Xing Gu

John B Robbins

David J Lim

A conjugate vaccine for Nontypeable comprising lipooligosaccharide from which esterified fatty acids have been removed conjugated to an immunogenic carrier. The vaccine is useful for prevention of otitis media and respiratory infections in mammals.

Conjugate vaccine for nontypeable Haemophilus influenzae

A conjugate vaccine for comprising lipooligosaccharide which does not contain a lacto-N-tetraose antigen from which at least one primary O-linked fatty acid has been removed conjugated to an immunogenic carrier. The vaccine is useful for prevention of meningitis and septic shock in mammals.

Conjugate vaccine for Neisseria meningitidis

A conjugate vaccine for Nontypeable,comprising lipooligosaccharide from which esterified fatty acids have been removed conjugated to an immunogenic carrier. The vaccine is useful for prevention of otitis media and respiratory infections in mammals.

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Bethesda, MD, United States of America

Chao-Ming Tsai