Compagnie Gervais Danone

Chantal Cayuela

Jean-Michel Antoine

Marie-Christine Degivry

Eric Postaire

Germain Trugnan

Miguel Freitas

James M Krueger

Nathalie Dugas

Christian Latge

Donna Hartley

Michael J Pabst

The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteria, which consists in measuring the average fluorescence intensity variation of HT29-MTX cells incubated in the presence of a lectin coupled with a fluorochrome after being in contact with the supernatant of the strain concerned. Said lactic acid bacteria strains can be used, optionally in the form of their active fraction, for preparing food compositions or medicines or food supplements, modulating glycosylation of glycoproteins of intestinal epithelial cells.

Microorganisms having intestinal cell surface glycosylation modulating action

The invention concerns lactic acid bacteria strains capable of regulating the production of NO and inflammatory cytokines by enterocytes, depending on the inflammatory condition of said enterocytes. The strains can also be incorporated in food supplements such as fermented dairy products used for regulating inflammatory response and non-specific immunity.

Selection and uses of lactic acid bacteria strains modulating non-specific immunity

Micro-organisms with glycosylation modulating action of intestinal cell surface

The invention concerns lactic acid bacteria with anxiolytic properties and not inducing sedative effect. Said lactic acid bacteria are useful in particular for preparing foods or medicines.

Lactic acid bacteria with anxiolytic properties and uses thereof

A method of improving sleep in a mammal having a sleep disorder is disclosed. The method includes identifying the mammal having a sleep disorder and then administering CNCM I-2274, CNCM I-2132, CNCM I-2275, CNCM I-1520, CNCM I-2272 or mixtures thereof. The method increases the length of the non rapid eye movement sleep phase and decreases the length of the rapid eye movement sleep phase. The bacteria can be administered in an orally consumable food product or a dietary supplement.

Administering bacteria to improve sleep

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Paris, France

Chantal Cayuela