Sanofi

Sanofi-aventis

Chantal Alcouffe

Corentin Herbert

Gilbert Lassalle

Alain Badorc

Francoise Bono

Marie-Francoise Bordes

Reinhard Kirsch

Jean-Marc Herbert

Jacques Mauger

Nathalie Guillo

Françoise Bono

Kirsten Bjegarde

Corentin Hebert

Gilbert Lassale

Marie-Françoise Bordes

The invention relates to FGF-inhibiting pyrazolopyrimidine derivatives of general formula (I) to a process for preparing them and to the therapeutic use thereof.

Pyrazolopyridine derivatives, preparation process therefor and therapeutic use thereof

The invention relates to the use of compounds corresponding to formula (I) in which Rand Rtogether form, with the carbon atoms of the phenyl nucleus to which they are attached, a 6-membered nitrogenous heterocycle corresponding to one of the formulae (A), (B) and (C) in which the wavy lines represent the phenyl nucleus to which Rand Rare attached, or of a pharmaceutically acceptable salt thereof, for preparing a medicament for the treatment of bladder cancer. 

Therapeutic use of imidazopyridine derivatives

The invention relates to the use of compounds corresponding to formula (I), or a pharmaceutically acceptable salt thereof, for preparing a medicament for the treatment of bladder cancer. 

Pyrazolopyridine derivatives for use in the treatment of bladder cancer

The invention relates to compounds corresponding to formula (I):  in which the wavy lines represent the phenyl nucleus to which Rand Rare attached. Preparation process and therapeutic use.

Imidazopyridine derivatives, process for preparation thereof and therapeutic use thereof

Indolizine derivatives, process for the preparation thereof and therapeutic use thereof

The invention concerns compounds of formula I, a method for preparing said compounds, pharmaceutical compositions containing same and the therapeutic uses thereof. 

Imidazo[1,5-a]pyridine derivatives, method for preparing same and pharmaceutical compositions containing same

Imidazo[1,5-a] pyridine derivatives, method for preparing same and pharmaceutical compositions containing same

The invention is directed to a compound of formula I, wherein R, R, R, Rand Rare as defined herein, or a pharmaceutically acceptable salt thereof, and its pharmaceutically composition, preparation and uses as an inhibitor of FGFs (fibroblast growth factors).

Substituted indolizine 1,2,3,6,7,8 derivatives, FGFs inhibitors, a method for the preparation thereof and pharmaceutical compositions containing said derivatives

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Paris, France

Chantal Alcouffe