Samsung Electronics Co., Ltd.

Samsung Bioepis Co., Ltd.

Chanmoo Lee

Youngsoo Kim

Mi Young Cho

Min-Kyung Kim

Su Jeong Hwang

Sangjoon Park

In Suk Choi

A fusion polynucleotide including a murine CMV promoter and an intron, a recombinant vector including the fusion polynucleotide and a gene encoding a polypeptide of interest, a recombinant cell including the recombinant vector, and a method of producing a polypeptide of interest using the recombinant vector and/or the recombinant cell.

Fusion polynucleotide containing murine CMV promoter and method of preparing a polypeptide of interest using the same

Disclosed is a method of producing 3-hydroxypropionic acid comprising the step of culturing recombinant microorganism comprising a nucleic acid sequence encoding-derived glycerol dehydratase, and a nucleic acid sequence encoding dehydrogenase, which converts 3-hydroxypropionaldehyde into 3-hydroxypropionic acid, and a recombinant microorganism used therefor. According to the present invention, the production of 3-hydroxypropionic acid remarkably increases and the production amount of 1,3-propanediol (1,3-PDO), which is generated as by-products when producing 3-hydroxypropionic acid, remarkably decreases, compared to known recombinant microorganisms comprising gene expressing-derived Vitamin B-dependent glycerol dehydratase.

3-hydroxypropionic acid-producing recombinant microorganism and method of producing 3-hydroxypropionic acid using the same

Growing community of inventors

Gwacheon-si, South Korea

Chanmoo Lee