Jiangsu Hengrui Medicine Company Ltd.

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Shanghai Hengrui Pharmaceutical Co., Ltd.

Changyong Yang

Lianshan Zhang

Guoqing Cao

Yong Guo

Xing Sun

Xiaoxing Huang

Piaoyang Sun

Jiahua Jiang

Cheng Liao

Xiaohua Wu

Qing Yang

Jianjun Zou

Quanren Wang

Ke Ma

Dingwei Ye

Disclosed is the use of a combination of an anti-PD-1 antibody and a VEGFR inhibitor in the preparation of a drug for treating cancers.

Use of combination of anti-PD-1 antibody and VEGFR inhibitor in preparation of drug for treating cancers

The present disclosure provides the use of an anti-PD-1 antibody in combination with famitinib in the preparation of a drug for treating tumors. In the present technical solution, toxicity is controllable and tolerable. At the same time, the described drug combination effectively reduces adverse reactions to the anti-PD-1 antibody, such as the occurrence of reactive capillary endothelial proliferation.

Use of anti-PD-1 antibody in combination with famitinib in preparation of drug for treating tumors

Disclosed is the use of a KOR agonist in combination with a MOR agonist in preparing a drug for treating pain. The KOR agonist is selected from a compound as shown in the general formula (I), and the MOR agonist is selected from a compound as shown in the general formula (II), wherein the definitions of each substituent in the general formula (I) and (II) are the same as defined in the description. 

Use of KOR agonist in combination with MOR agonist in preparing drug for treating pain

This application describes a use of an EZH2 inhibitor combined with a BTK inhibitor in preparing a drug for treating a tumor is described.

Use of EZH2 inhibitor combined with BTK inhibitor in preparing drug for treating tumor

A combination of a VEGFR inhibitor and a PARP inhibitor is described. In particular, this combination can be used in the preparation of a medicament for treating gastric cancer.

Use of combination of VEGFR inhibitor and PARP inhibitor in preparation of medicament for treating gastric cancer

Growing community of inventors

Jiangsu, China

Changyong Yang