Life Technologies Corporation

Los Alamos National Security, LLC

Other

Chang Zhong

Jason Yingjie Liu

Michael Harrold

Lori Hennessy

Jennifer Suzanne Martinez

Yuping Y Bao

R Brian Dyer

Dung M Vu

Steven Menchen

Julio Mulero

Chandani Patel

Methods for human identification using polymorphisms in the Penta E short tandem repeat locus are significant in preventing allelic drop out. An exemplary method encompasses (a) contacting a first primer to a nucleic acid sample to be analyzed, (b) contacting a second primer to the nucleic acid sample, and (c) subjecting the nucleic acid sample, the first primer, and the second primer to an amplification reaction, and thereby forming an amplification product. The first primer, the second primer, or both the first and second primers can be labeled with a non-nucleic-acid label. Additionally, or alternatively, the amplification product can include an adenosine at position 14 from the 5' end of SEQ ID NO:1, a thymidine at position 21 from the 5&#x2032; end of SEQ ID NO:2, or both an adenine at position 14 and a thymidine at position 21 from the 5&#x2032; end of SEQ ID NO:3.

Penta E polymorphisms for human identification

Disclosed herein are mesylate containing compositions, methods of use of such compositions and kits of components encompassing such compositions for improving the amplification of nucleic acids, especially in the presence of enzymatic inhibitors. These find particular use in forensic and environmental analyses. The instant disclosure provides new compositions, methods and kits of components for overcoming PCR inhibition. In some embodiments disclosed herein is a PCR master mix, the PCR master mix encompassing a mesylate.

Mesylate based master mix

Disclosed herein are methods and compositions for human identification using polymorphisms in the Penta E short tandem repeat locus. These newly disclosed polymorphisms are significant in preventing allelic drop out.

Penta e polymorphisms for human identification

Systems, methods, and kits are disclosed for collection, labeling and analyzing biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature of an individual. Such devices and methods are used in forensic, human identification, access control and screening technologies to rapidly process an individual's identity or determine the identity of an individual.

Simultaneous acquisition of biometric data and nucleic acid

Fluorescent metal nanoclusters were prepared.

Growing community of inventors

Stanford, CA, United States of America

Chang Zhong