Sk Chemicals Co., Ltd.

Ahn-Gook Pharmaceutical Co., Ltd.

Sunkyong Industries Ltd.

Chang-Kyun Han

Wie-Jong Kwak

Jin Auh

Young-June Shin

Chang-Hwan Kim

Soo-Im Chang

Sung-Hum Yeon

Keun Ryu

Yong-Baik Cho

Joo Hyon Kim

Min-Ki Shin

Se Jun Yun

Jong-Wook Lee

Bongcheol Kim

Guang-Jin Im

Tae Kon Kim

Hunseung Yoo

Hae In Rhee

Soomin Lee

Hyo-Jin Moon

In Ho Jung

Wonrack Choi

Sung-Min Kim

Jung-Woo Seo

Jung Bum Yi

Yong-baik Cho

Key An Um

Kang-Jin Lee

So Yoon Lee

Do Seung Kum

Taek-Soo Kim

Tae-Hoo Yi

Dong-Oh Han

Ki Won Joung

Hwan-su Kim

Jae-suk An

Taek-soo Kim

Bong Cheol Kim

Hee Jae Shin

Soon Keun Lee

ChilMann Jung

Gi Uk Jang

Eun Jung Noh

Kiwon Joung

Kang-Hyun Leem

Hye Yeon Baek

Ho-Young Kwak

Jun-Seok Lee

Ji-Hye Lee

Seung-In Choe

Chil Mann Jung

Taek Su Kim

Hun Seung Yoo

Keun Ho Ryu

Tae Kon 348-11 Hyundai Byeoksan Apt 886-1 Kim

Chilmann C-103 Milae House Jung

The present invention relates to an extract isolated from Sophorae Radix useful for prevention and treatment of respiratory diseases. More specifically, the present invention relates to a pharmaceutical drug comprising the Sophorae Radix extract having excellent effects of inhibiting airway contraction, respiratory infections, 5-lipoxygenase activity, phosphodiesterase 4 activity, airway hyper-responsiveness and airway remodeling; antagonistic activity against leukotriene D4; and an antitussive effect, thus being useful for prevention and treatment of respiratory diseases such as asthma, acute or chronic bronchitis, allergic rhinitis, acute upper respiratory infections and acute lower respiratory infections, and the like.

Sophorae Radix extract for prevention and treatment of respiratory diseases

A composition for suppressing cough, removing sputum, preventing and/or treating a respiratory disease comprising an extract of Coptidis rhizoma or a combined extract of Coptidis rhizoma with ivy leaf as an active ingredient, and a method of suppressing cough, removing sputum, and/or preventing and/or treating respiratory disease using the composition, are provided.

Extract ofand novel use thereof in treating respiratory disease

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The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.

Triterpene compounds which are effective on improvement of brain function

The present invention relates to a herbal drug composition for cartilage protection comprising plant extracts of Clematis Radix, Trichosanthis Radix, and Prunellae Spica and an optimal content of rosmarinic acid to: (i) alleviate pains; (ii) inhibit the acute/chronic inflammation, platelet/whole blood aggregation, immunocyte (B-lymphcyte and T-lymphcyte) proliferation, inflammation-inducing enzyme activities, and enzyme activities associated with degradation of joint tissue; (iii) scavenge activity of toxic active oxygen radicals; and (iv) further provide excellent cartilage protection activity to be effectively used as an anti-inflammatory agent with analgesic effects, blood circulation enhancer, arthritis therapeutic agent and cartilage protective.

Herbal drug composition for cartilage protection

The present invention relates to a novel use of herbal extracts in a pharmaceutical composition for prevention and treatment of nephritis and, more particularly, to a pharmaceutical composition and a health functional food for prevention and/or treatment of nephritis that contains at least one herbal extract selected from the group consisting of a Crataegi Fructus extract, a Cinnamomi Cortex extract, a Prunella Spica extract, and an Equiseti Herba extract, a method for prevention and/or treatment of nephritis using the herbal extract, and a use of the herbal extract in preparation of a composition for prevention and/or treatment of nephritis. The herbal extract has a good therapeutic effect for nephritis on a nephritis model of which the nephritis is induced by a drug such as gentamicin, cisplatin, etc., and a good inhibitory activity on the growth of mesangial cells in kidneys, thereby providing a very useful means for prevention and/or treatment of nephritis.

Pharmaceutical composition containing herbal extract for prevention or treatment of nephritis

A use an extract ofor a combined extract ofandas an active ingredient for preventing and/or treating periodontal disease is provided. The extract ofor a combined extract ofandhas activities to stimulate anti-inflammation, osteoblast differentiation and alveolar bone regeneration, and to prevent the alveolar bone destruction, thereby being effective for the prevention and/or treatment of periodontal disease.

Preventing or treating periodontal diseases by herbal extract

A composition for suppressing cough, removing sputum, preventing and/or treating a respiratory disease comprising an extract ofor a combined extract ofwith ivy leaf as an active ingredient, and a method of suppressing cough, removing sputum, and/or preventing and/or treating respiratory disease using the composition, are provided.

The present invention relates to a Momordicae semen extract effective in the prevention and treatment of gastritis or gastric ulcer andsaponin I isolated therefrom. The Momordicae semen extract and thesaponin I isolated therefrom is effective in the prevention and treatment of gastritis or gastric ulcer since they prevent the damage of the gastric mucosa caused by alcohols and inhibit the secretion of gastric acid.teh

This invention relates to Pulsatillae Radix extract for improving brain functions. More specifically, this invention relates to Pulsatillae Radix extract, its active fractions and a pharmaceutical product and a health food containing the same respectively having a protective activity against neurotoxicity and a growth inhibitory effect induced by beta-amyloid, an anti-oxidizing effect, a neuron proliferating effect and improving memory thereby effective in improving brain functions such as Mild Cognitive Impairment and dementia.

Disclosed is a topical formulation for preventing or treating acne, in particular to a topical formulation for preventing or treating acne through the antimicrobial activity of the formulation against acne-causing bacteria,, inhibition of excess production of sebum by inhibition of excess production of sebum by inhibition of 5&#x3b1;-reductase, inhibition of comedo, keratolysis and anti-inflammatory action, which comprises extract obtained from at least one oriental medicine selected from the group consisting ofand

Topical formulation for prevention and treatment of acne

Disclosed is a method for extracting and purifying active constituents from honeysuckle (Thunb.) and its use. More particularly, this invention relates to an extraction and purification method of active constituents including sweroside from for honeysuckle stem (stem of honeysuckle where leaves are removed) by removing tannins, hardly soluble flavonoids, saponins, and the like. Thus obtained active constituents have better anti-inflammatory and analgesic effect, are safer and more stable than the conventional active constituents obtained from honeysuckle flower or honeysuckle leaves, and include sweroside which is an effective active ingredient of anti-inflammatory and analgesic drug.

This invention to a process of extracting and purifying biologically effective ingredients from combined medicinal plants and their plant extract composition and more particularly, to a process for effective extracting and purifying the biologically effective ingredients by mixing Clematis Radix, Trichosanthes root and Prunella Herba in a certain ratio, being useful for alleviating acute/chronic inflammation and also for inhibiting platelet/whole blood aggregation, abnormally proliferated immunocytes (e.g., B-lymphocyte, T-lymphocyte), inflammation-inducing enzymes (5-Lipoxygenase, Cyclooxygenase-I, Cyclooxygenase-II) and also scavenging activity on toxic active oxygen species when compared to a single plant extracts, together with their extract composition, which may be effectively used as an anti-inflammatory agent with analgesic effects, rheumatoid arthritis drug and agents for improving peripheral blood circulation.

Process of extracting and purifying biologically effective ingredients

Growing community of inventors

Seoul, South Korea

Chang-Kyun Han