Amorepacific Corporation

Chang Geun Yi

Jeong Hwan Kim

Do Hoon Kim

Won Seok Park

Jong Hee Park

Eun Jung An

Hong Ju Shin

Jae Sung Hwang

Jin Woong Kim

Yong Jin Kim

Yung Hyup Joo

Hyung Jun Lim

Yongjin Kim

Jon Hwan Lee

Heung Soo Baek

Hong-Ju Shin

Jong Won Shim

Mi Jin Kim

Jung A Seo

5-Adamantan-1-yl-N-(2,4-dihydroxybenzyl)-2,4-dimethoxybenzamide disclosed in the present disclosure lacks toxicity and can exhibit superior anti-inflammatory effect. It exhibits superior anti-inflammatory effect, for example, by inhibiting the production of one or more of NO and PGE2, by inhibiting the activity of one or more of the transcription factors NF-&#x3ba;B and AP-1 or by inhibiting proinflammatory cytokines such as IL-1&#x3b2;.

Composition for anti-inflammation containing 5-adamantan-1-yl-N-(2,4-dihydroxy-benzyl)-2,4-dimethoxy-benzamide

Provided are: a multi-layered lamellar granule comprising a nucleating agent, a ceramide-containing artificial stratum corneum lipid lamellar layer which encases the nucleating agent and a polymer layer disposed on the artificial stratum corneum lipid lamellar layer; and an external skin application composition comprising the same. The external skin application composition shows improved moisturizing and barrier repair capabilities when applied to the skin, which can be advantageously used in cosmetics and pharmaceuticals.

Multi-layered lamellar granule and skin external application composition containing same

Provided is a pseudolipid complex mixture comprising a pseudoceramide and a stearic acid and an external skin application composition comprising the same. The complex mixture has improved phase stability and a structure similar to that of the stratum corneum which can retain water and other beneficial materials, and accordingly the composition comprising the same can be used as an external skin application composition having improved moisturization and barrier repair capabilities.

Pseudolipid complex mixture and a skin external application composition containing same

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Yongin-si, South Korea

Chang Geun Yi