Chung Yuan Christian University

National Defense Medical Center

National Defensive Medical Center

Chang-Chi Lin

Tzong-Yuan Wu

Ying-Ju Chen

Szu-Cheng Kuo

Yi-Ting Lin

Chien-Ling Su

Der-Jiang Chiao

Pei-Yun Shu

Shu-Fen Chang

Meng-Hung Tsai

Szu-Chia Lai

Yu-Yine Huang

Jiunn-Jye Wey

Yu-Ming Wang

Disclosed herein are recombinant baculoviruses suitable for detecting the presence of arthropod-borne viruses in a biological sample of a test subject. The information derived from the detection may also be used to render a diagnosis on whether the test subject is infected with the arthropod-borne viruses or not, so that proper course of treatment may be assigned to the subject.

Method of detecting antibodies against JEV or ZIKV using recombinant baculoviruses expressing prM/e

Recombinant baculoviruses and their uses in detecting arthropod-borne virus

The present invention relates to anti-virus dengue virus antibodies and applications thereof. Specifically, the anti-virus dengue virus antibodies of the present invention are serotype specific and useful for specific detection and differentiation of various dengue virus serotypes in a biological sample. The present invention also provide methods and kits for detecting dengue virus and methods and compositions for use in diagnosis and treatment of dengue virus disease using the anti-virus dengue virus antibodies as described herein.

Anti-dengue virus antibodies and applications thereof

Disclosed herein is a method for the treatment of an infection with, or disease caused by, Chikungunya virus in a subject. The method includes administering to the subject a therapeutically effective amount of suramin as the active agent.

Method for treating Chikungunya virus infection

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Taipei, Taiwan

Chang-Chi Lin