The Procter Gamble Company

Other

The Gillette Company

Genencor International, Inc.

Chanchal Kumar Ghosh

Donn N Rubingh

Eugene Paul Gosselink

Volker Schellenberger

Ayrookaran J Poulose

Alfred Busch

James T Kellis, Jr

Robert Mark Caldwell

Katherine D Collier

Michael Stanford Showell

Christian G Paech

William Michael Scheper

Alan David Willey

Michael E Burns

Richard Timothy Hartshorn

Robert Henry Rohrbaugh

John David Carter

Richard Ray Bott

John Christian Haught

Andre Cesar Baeck

Thomas P Graycar

Aleksey Mikhailovich Pinyayev

Ping Wang

Frank William Denome

Gayle Marie Frankenbach

Jiten Odhavji Dihora

Brian Joseph Loughnane

Jianjun Justin Li

Kenneth Nathan Price

Peter Robert Foley

Brian Xiaoqing Song

John Geoffrey Chan

Gordon Gerald Guay

Jonathan Robert Cetti

Chandrika Kasturi

Howard David Hutton, Iii

Satyanarayana Majeti

Bobby Lee Barnett

Philip Frederick Brode, Iii

Joanne Nadherny

Donald P Naki

Ryohei Ohtani

Michael Ray McDonald

Edward Eugene Getty

Stephen Andras Kovacs

David Neil DiGiulio

Andr&eacute; Cesar Baeck

Lori Jean Wilson

Philip F Brode

James Iain Kinloch

Zerlina Guzdar Dubois

Alan Scott Goldstein

Randall Alan Watson

Virginia Tzung-Hwei Hutchins

Marc Adam Flickinger

Glenn Thomas Jordan, Iv

Jerome Howard Collins

Dean Arthur Zimmerman

Ronald David Turner

Eric Altman Goulbourne, Jr

Helen Frances O'Connor

Steven Edward Witt

Ke Ming Quan

Brenda Frances Bennie

Morgan Thomas Leahy

Douglas Craig Scott

Ronald Edward Pegoli

Kevin Max Labitzke

Marc Francedillaois Evers

Lowen Robert Morrison

Neha Kapur

Heather Anne Liddle

Sanjeev Krishnadas Manohar

Elizabeth Ann Alam

André Cesar Baeck

Mairi Campbell

Catherine Michelle Quinn

Lowen Robert Morrision, Jr

Andr&eacute;Cesar Baeck

Robert Wayne Glenn

Eric Altman Goulbourne

Ali Abdelaziz Alwattari

Wang Room 608 7Th Building Ping

Stephan Andras Kovas

Ping Room 608 7Th Bldg Qian He Jian Yuan Wang

James T Kellis

A sensor-responsive toothbrush that can adjust its output or operation depending upon information received by one or more sensors incorporated in the toothbrush or as selected by a user. The information typically relates to certain conditions or the presence of particular substances or agents within or outside of the oral cavity. The sensor-responsive toothbrush also includes one or more responsive output components that provide a responsive output in response to the sensed information. A method of providing an oral care benefit, comprising steps of: activating a toothbrush comprising a sensor; detecting a sensor input with the sensor; and initiating a responsive output from the toothbrush in response to the sensor input.

Sensor responsive electric toothbrushes and methods of use

An electric toothbrush having a handle, a head, and a neck extending between the handle and the head is disclosed. The handle has a hollow interior region having a motor and an electrical power source. The head includes an ultrasonic transducer and a bristle field. The ultrasonic transducer is in electrical communication with the electrical power source, and a shaft is operatively connected to the motor for moving the bristle field.

Electric toothbrush comprising an electrically powered element

Compositions for treating fabric articles, especially articles of clothing, linens and drapery, wherein the compositions provide improved cleaning of soils from and/or care of and/or treatment of fabric articles, especially while providing an antimicrobial agent.

Fabric care compositions for lipophilic fluid systems containing an antimicrobial agent

Compositions for treating fabric articles, especially articles of clothing, linens and drapery, wherein the compositions provide improved cleaning of soils from and/or care of and/or treatment of fabric articles, especially while providing superior garment care for articles sensitive to water as compared to conventional fabric article treating compositions, are provided.

Fabric care compositions for lipophilic fluid systems incorporating an antimicrobial agent

Rinse aid materials for coating, coating compositions, methods and articles of manufacture for use in automatic dishwashing appliances comprising a nanoparticle system or employing the same to impart surface modifying benefits for all types of dishware surfaces are disclosed. In some embodiments, dispersement of nanoparticles in a suitable carrier medium allows for the creation of rinse aid surface coating compositions, methods and articles of manufacture that create multi-use benefits to modified dishware surfaces. These surface modifications can produce long lasting or semi-permanent multi-use benefits that include at least one of the following improved surface properties: wetting and sheeting, uniform drying, anti-spotting, anti-staining, anti-filming, self cleaning, and durability benefits, relative to dishware surfaces unmodified with such nanoparticle systems. In some embodiments, actively curing the rinse aid surface coating composition on the dishware surfaces, including, but not limited to by radiative heating the air surrounding the dishware surface with the coating thereon can be used to increase the durability of the dishware surface coating.

Rinse aid surface coating compositions for modifying dishware surfaces

Materials for coating, coating compositions, methods and articles of manufacture comprising a nanoparticle system or employing the same to impart surface modifying benefits for all types of hard surfaces are disclosed. In some embodiments, dispersement of nanoparticles in a suitable carrier medium allows for the creation of coating compositions, methods and articles of manufacture that create multi-use benefits to modified hard surfaces. In some embodiments, actively curing the coating composition on the hard surfaces, including, but not limited to by radiative heating the air surrounding the hard surface with the coating thereon can be used to increase the durability of the hard surface coating.

Coatings for modifying hard surfaces and processes for applying the same

The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 ofsubtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 ofsubtilisin; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a subtitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 ofsubtilisin; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 ofsubtilisin; and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.

Cleaning compositions containing multiply-substituted protease variants

The present invention relates to bleaching compositions comprising a protease variant. One bleaching composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of subtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274, and 275 of subtilisin; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a substitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265, or 274 of subtilisin, a bleaching agent; and one or more cleaning adjunct materials. Another bleaching composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of subtilisin; a bleaching agent; and one or more cleaning adjunct materials. Methods for using the bleaching compositions are also provided.

Bleaching compositions comprising multiply-substituted protease variants

A hard-surface cleaning composition for removing cooked-, baked-, or burnt-on food soil from cookware and tableware, the composition comprising a solvent system, wherein said solvent system comprises: a mono-, di- or tri-ethylene glycol phenyl ether or a mixture thereof; and a di- or tri-propylene glycol alkyl ether having an alkyl chain containing of from about 1 to about 5 carbon atoms or a mixture thereof.

Hard surface cleaning composition comprising a solvent system

A method of removing cooked-, baked-, or burnt-on food soil from cookware and tableware comprising washing the cookware/tableware in an automatic dishwashing machine in the presence of an organic solvent system having a volatile organic content of less than about 50% by weight and a wash liquor concentration of from about 100 ppm to about 10000 ppm. The method includes the storage and delivery of organic solvent compositions and dishwashing detergent composition from multi-compartment containers. The method provides excellent removal of stubborn soils which are very difficult to remove in a conventional automatic dishwashing process.

Cleaning composition

The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 of ; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a subtitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of ; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of ; and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.

Laundry detergent compositions comprising zwitterionic polyamines and xyloglucanase

The present invention relates to subtilisin BPN&prime; variants comprising at least one or more amino acid positions having a different amino acid than that occurring in wild-type subtilisin BPN&prime; (i.e., substitution) at specifically identified positions, whereby the BPN&prime; variant has decreased adsorption to, and increased hydrolysis of, an insoluble substrate as compared to wild-type subtilisin BPN&prime;. The present invention further relates to various cleaning compositions comprising such BPN&prime; variants.

BPN&prime; variants having decreased adsorption and increased hydrolysis

The present invention relates to subtilisin BPN&prime; variants having a modified amino acid sequence of wild-type BPN&prime; amino acid sequence, the wild-type amino acid sequence comprising a first loop region, a second loop region, a third loop region, a fourth loop region and a fifth loop region; wherein the modified amino acid sequence comprises different amino acids than that occurring in wild-type subtilisin BPN&prime; (i.e., substitution) at specifically identified positions in one or more of the loop regions whereby the BPN&prime; variant has decreased adsorption to, and increased hydrolysis of, an insoluble substrate as compared to the wild-type subtilisin BPN&prime;. The present invention also relates to the genes encoding such subtilisin BPN&prime; variants. The present invention also relates to compositions comprising such subtilisin BPN&prime; variants for cleaning a variety of surfaces.

BPN&prime; variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted

Growing community of inventors

West Chester, OH, United States of America

Chanchal Kumar Ghosh