Yuhan Corporation

Chan-Sun Park

Dong-Hoon Kim

Ho-Woong Kang

Young-Ae Yoon

Jae-Gyu Kim

Myung-Hun Cha

Byung-Nak Ahn

Suk-Won Yoon

Hyouk-Woo Lee

Sun-Young Jang

Eui-Chul Lee

Su-Youn Nam

Eun-Hye Jung

Seok-Hee Han

Youn Hur

Jin-Hwi Park

Jong-Gyun Kim

Dong-hyun Kim

Ho-jin Lee

Young-hwan Kim

Young-Hwan Kim

Chun-Ho Lee

Se-Woong Oh

Heui-Il Kang

Tae-Dong Han

Heui Ii Kang

Jae-Eun Joo

Su-Bin Choi

Won-Ee Chong

Hyok-Jun Cho

Gyu-Jin Lee

Jun-Chul Park

Hee-Jae Tak

Seung-Yub Shin

Koo-Yeon Lee

Ji-Yeong Gal

Young-Ae 502-1006 Munrae Hyundai 5Cha Apt Yoon

Hyouk-Woo 405-202 Jugong Greenvil Apt Lee

Myung-Hun 105-1601 Jugong Tteuranchae Apt Cha

Ryong Choi

The present invention provides a quinazoline derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof. The quinazoline derivative or its pharmaceutically acceptable salt has a selective inhibitory activity against the phosphatidylinositol 3-kinase delta subunit, and therefore can be usefully applied for preventing or treating cancer, along with avoiding side effects such as lymphopenia-associated inflammatory responses.

Quinazoline derivative or its salt and pharmaceutical composition comprising the same

The present invention provides a benzo[d]thiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The benzo[d]thiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the benzo[d]thiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis.

Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same

The present invention provides a 4,5-dihydro-1H-pyrazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The 4,5-dihydro-1H-pyrazole derivative or its pharmaceutically acceptable salt effectively increases the LXR transcriptional activity, and therefore can be usefully applied for preventing or treating a dysfunction in cholesterol metabolism, such as cholesterol gallstone, hyperlipidemia, or coronary atherosclerosis.

4,5-dihydro-1H-pyrazole derivative or salts thereof, and pharmaceutical composition comprising same

The present invention provides novel pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.

Pyrrolo[2,3-C]pyridine derivatives and processes for the preparation thereof

Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof

Growing community of inventors

Gyeonggi-do, South Korea

Chan-Sun Park