Sk Biopharmaceuticals Co., Ltd.

Medifron Dbt Co., Ltd.

Daewoong Pharmaceutical Co., Ltd.

Chan Mi Joung

Young Koo Jang

Cheol Young Maeng

Ji Won Lee

Hye Won Shin

Eun Jung Yi

Su Bong Cha

Ji Yeon Kim

Ju Young Lee

Hee Sun Kim

Dong Wook Kang

Young Ho Kim

Eun Ju Choi

Jee Woo Lee

Nahm Ryune Cho

Yong Je Shin

Jin Yong Chung

Eun Joo Nam

Hye Kyung Min

Hyo Jun Jung

Eun Ju Ryu

Hee Jin Ha

Soo Bong Cha

Yong Gil Kim

Jong Sil Park

Chun Eung Park

Seung Mo Ham

Seung Nam Han

Sun Gwan Hwang

Hwa Ryun Cha

The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same

The present invention relates to a blend for prevention, mitigation, or treatment of schizophrenia, the blend containing a carbamate compound of chemical formula 1, or a pharmaceutically acceptable salt, solvate, or hydrate thereof and, more specifically, to a blend and a pharmaceutical composition each containing a carbamate compound of chemical formula 1 and aripiprazole, and to a use thereof for treating schizophrenia.

Blend containing carbamate compound for prevention, mitigation, or treatment of schizophrenia

The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same:  The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

A pyridone derivative compound and a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof, and a preventive or therapeutic pharmaceutical composition for cognitive disorders that includes the pyridone derivative compound or a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof.

Pharmaceutical composition comprising pyridone derivatives

The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.

Benzofuran type derivatives, a composition comprising the same for treating or preventing cognitive dysfunction and the use thereof

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Daejeon, South Korea

Chan Mi Joung