University of Iowa Research Foundation

Medical 21, Inc.

Chaid D Schwarz

Vijay Kumar

Eric E Solien

Madhavan L Raghavan

Jeff R Vreeman

Manuel A Villafana

A composite implant having multiple open-pore biodegradable polymer layers mechanically supported by a permanent structure positioned between adjacent polymer layers drives a native response for cellular infiltration, which facilitates progressive cellular-driven remodeling, cellular organization, and native extra-cellular matrix (ECM) deposition. This leads to endogenous tissue remodeling of the implant over time. The support structure provides mechanical support to the implant to effectively carry impressed mechanical load while the remodeling process is ongoing. The polymer layers are formulated to fully degrade over time, leaving only the new native tissue supported by the permanent support structure.

Composite implant

Described herein are methods of producing biosynthetic bacterial cellulose membranes having improved characteristics that are advantageous for use in various biological applications, including medicine.

Methods of producing biosynthetic bacterial cellulose membranes

Growing community of inventors

Medina, MN, United States of America

Chaid D Schwarz