Abbott Laboratories Corporation

Abbott Laboratory

Chadwick M Dunn

Mark A Talmer

Charles Michael Galitz

Stephen L Herchenbach

Scott G Safar

Cass J Grandone

Julius J Toth

Eric B Shain

Patrick P Fritchie

James T Holen

Ronald E Kukla

James T Tyranski

Jack F Ramsey

Jimmy D McCoy

Neal T Sleszynski

Richard C East

Adrian John Murray

Robert Paul Luoma, Ii

Timothy P Henning

Michael G Lowery

David Charles Arnquist

Joseph P Skinner

Gregory E Gardner

Larry L McDowell

Robert C Gray

Grady Barnes, Iii

James E Mitchell

Gary L Zuck

Sonal Sadaria Nana

Timothy J Patno

David W Murray

Robert J Nelson

Richard D Button

James F Mitchell

Daniel J Harris

Kris T Ludington

Austin Lines

Eric D Yeaton

Larry L Mcdowell

Jody L Keck

Wesley W Addison Ii

Michael Lowrey

Stephen Herchenbach

Magnetic handling structure comprising a retractable magnet and a probe for the manipulation of magnetic particles in biological samples and methods of handling magnetic particles in biological samples.

Structure and method for handling magnetic particles in biological assays

A reaction vessel with a bottom drain opening supporting a selected unpressured head of fluid by the surface tension of the fluid. A device processing zone includes a support for spaced rows of reaction vessels, passages communicating with their drain openings of supported vessels, and a pressure source for selectively draining fluid through the drain openings. Generally horizontal bar magnets are supported for selected vertical movement between the vessel rows. A dispensing head has X discharge openings selectively positionable over X selected reaction vessels. A metering pump mechanism selectively meters X a selected quantity of fluid a bulk supply (where X is at least four), and selectively pumps the metered selected quantities through the drain openings to the selected reaction vessels. Methods of drawing fluid from the vessels using the pressure source, and moving the magnets to form a pellet of analyte are also included.

Apparatus and method for handling fluids for analysis

Magnetic handling structure () comprising a retractable magnet () and a probe () for the manipulation of magnetic particles in biological samples and methods of handling magnetic particles in biological samples.

The embodiments disclosed relate to determination of an item of interest in a sample. One embodiment relates to a structure which comprises a process path. The process path comprises a process lane including a process step performance lane where a process step is performed, and a process step avoidance lane where the process step is avoided. A first prime mover is operatively connected with the process path for moving a container holding the sample along the process path. A first pipetting system is operatively associated with the process path for introducing the sample to the container. A second pipetting system is operatively associated with the process path for introducing a reagent to the container. A device is operatively connected with the process path and is selectively engagable with the container for mixing the sample and the reagent in the container. A second prime mover is operatively connected with the process path for selectively positioning the container in a selected one of the process step performance lane and the process step avoidance lane. A reader is operatively connected with the process path for determining the item of interest in the sample based upon a reaction between the sample and the reagent.

Structure for determination of item of interest in a sample

The embodiments disclosed relate to determination of an item of interest in a sample. In one method, a process path comprising a process lane including a process step performance lane where a process step is performed, and a process step avoidance lane where the process step is avoided is provided. A container holding the sample is moved along the process path. The sample is introduced to the container. A reagent is introduced to the container. The sample and the reagent are mixed in the container. The container is selectively positioned in a selected one of the process step performance lane and the process step avoidance lane. The item of interest in the sample is determined based upon a reaction between the sample and the reagent.

Method for determination of item of interest in a sample

Embodiments described herein provide methods of performing a process for determining an item of interest in a sample. In one embodiment, a container for holding the sample is accepted in a process lane where a process step is selectively automatically performed on the sample in the container. The process step is selectively automatically performed on the sample in the container. An effective length of the process lane is maintained constant while a physical length of the process lane is selectively varied.

Method of performing a process for determining an item of interest in a

An assay carrier for carrying and positioning a plurality of reaction cells each carrying a single assay, and for carrying and positioning a plurality of reagent packs, for use in selectively performing any one of a plurality of immunoassays on each of the plurality of cells in the carrier.

Carousel for assay specimen carrier

A kit comprising a modified carousel for carrying a plurality of reaction cells and a plurality of reagent packs is adapted to be installed as a replacement unit in single immunoassay instrumentation, providing an immunoassay instrument which is capable of selectively performing any one of a plurality of immunoassays on multiple reaction cells.

Retrofit kit for changing single immunoassay instrument to flexible

A carousel for carrying and positioning a plurality of assays and a plurality of reagent packs in an immunoassay testing apparatus is designed to direct warmed or heated air in a predetermined and controlled manner for maintaining the assays and reagent packs within a specified, controlled temperature range.

Heat and air flow control for assay carrier

Growing community of inventors

Janesville, WI, United States of America

Chadwick M Dunn