Cook Biotech, Inc.

Cook Medical Technologies LLC

Oregon Health & Science University

Chad S McAlexander

Umesh H Patel

Bhavin Shah

Michael C Hiles

Clay D Fette

Joesph W Zubik

Thomas A Osborne

Brian L Bates

Dusan Pavcnik

John A Kaufman

Jason P Hodde

Matthew R Graham

Likang Chin

Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.

Medical devices and methods useful for applying bolster material

Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures are used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the deployment of one or more vascular occlusion devices via a through-and-through percutaneous procedure that leaves the vascular occlusion device or devices in a through-and-through condition.

Vascular occlusion methods, systems and devices

Described are methods and systems for drying remodelable materials, such that selective regions of the remodelable materials have differing properties. Also described are medical graft products having selective regions of differing material properties. Advantageous remodelable materials include collagenous extracellular matrix material, such as small intestine submucosa.

Medical graft products with differing regions and methods and systems for producing the same

An apparatus for use with a surgical stapler to provide a reinforced surgical staple line. The apparatus includes an applicator that carries a first and second bioimplantable material connected by a hinge. An applicator clip may be provided to releasably secure the first and second bioimplantable material onto the applicator.

Apparatus and method for producing a reinforced surgical staple line

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West Lafayette, IN, United States of America

Chad S McAlexander