University of Notre Dame Du Lac

University System of Maryland

The University of New Mexico

Cedric Xinsheng Yu

Danny Ziyi Chen

Shuang Luan

Chao Wang

Xiaobo Sharon Hu

Xiaodong Wu

Matthew A Earl

Bo Zhou

Kevin Whitton

Provided herein are methods and systems for designing a radiation treatment for a subject using single arc dose painting. The methods and systems comprise an algorithm or a computer-readable product having the same, to plan the radiation treatment. The algorithm converts pairs of multiple leaf collimation (MLC) leaves to sets of leaf aperture sequences that form a shortest path single arc thereof where the pairs of MLC leaves each aligned to an intensity profile of densely-spaced radiation beams, and connects each single arc of leaf apertures to form a final treatment single arc. Also provided is a method for irradiating a tumor in a subject using single arc dose painting.

Single-arc dose painting for precision radiation therapy

Disclosed is an example method to calculate radiation dose. The method includes receiving a tissue matrix in which the tissue matrix includes a plurality of voxels. The example method also includes producing a first plurality of transport lines with a direction controller in which each transport line is indicative of a cone of irradiated energy, and calculating at least one radiation dose with at least one deposit engine substantially in parallel with producing a second plurality of transport lines with the direction controller.

Methods and apparatus for hardware based radiation dose calculation

The present invention provides a method comprising the following steps: (a) partitioning an intensity modulated beam into a set of sub-IMBs; and (b) partitioning the sub-IMBs into segments, wherein steps (a) and (b) introduce no machine delivery error. The present invention also provides a method comprising the following steps: (a) recursively partitioning an intensity modulated beam into plateaus; and (b) partitioning the plateaus into segments, wherein step (a) comprises determining a tradeoff between machine delivery error and the number of segments into which the plateaus will be partitioned in step (b).

Error control in algorithmic approach to step-and-shoot intensity modulated radiation therapy

The present invention provides a method comprising recursively partitioning an intensity modulated beam into plateaus; and partitioning the plateaus into segments. The present invention also provides a method for controlling administration of radiation therapy to a patient based on static leaf prescriptions. In addition, the present invention provides a method for partitioning an IMB.

Segmentation algorithmic approach to step-and-shoot intensity modulated radiation therapy

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Clarksville, MD, United States of America

Cedric Xinsheng Yu