Ossdsign Ab

Inossia Ab

Iknow-who Gmbh

Cecilia Persson

Håkan Engqvist

Wei Xia

Sigvald Harryson

Jun Luo

Alejandro Lopez

Injectable, ready-to-use two-paste cement-forming compositions comprise a first paste and a second paste. The first paste comprises a non-aqueous oil-based suspension of monocalcium phosphate monohydrate (MCPM) powder, at least one surfactant effective to improve compatibility of the oil and the MCPM, and an organic acid, with an oil to MCMP powder weight ratio of about 0.2 to about 0.5. The second paste comprises an aqueous suspension of &#x3b2;-tricalcium phosphate (&#x3b2;-TCP) powder and a gel-forming polymer, with a water to &#x3b2;-TCP powder weight ratio of about 0.3 to about 0.5. The molar ratio of &#x3b2;-TCP powder to MCPM powder is greater than 1. An article of manufacture comprises a first compartment in which the first paste is contained, and a second compartment in which the second paste is contained. The compositions are useful for bone repair or replacement.

Two-paste cement-forming compositions

The embodiments relate to an injectable composition for a bone cement material comprising a dry powder component, a liquid component and a modifier configured to modify a Young's modulus of the bone cement material. The modifier is linoleic acid or a derivative thereof and is present in a concentration of 0.1 to 12 v/v of the liquid component.

Acrylic cements for bone augmentation

Growing community of inventors

Uppsala, Sweden

Cecilia Persson