23andme, Inc.

Cecilia Lay

Erik E Karrer

Yu Chen

Germaine Fuh-Kelly

Yao-ming Huang

Louise Scharf

Wei-Jen Chung

Steven J Pitts

Jilean Beth Fenaux

The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD200R1 receptor protein (hu-CD200R1) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD200R1. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD200 binding to CD200R1.

Anti-CD200R1 antibodies and methods of use thereof

Growing community of inventors

Brisbane, CA, United States of America

Cecilia Lay