Codexis, Inc.

Catherine M Cho

Louis Clark

Benjamin Mijts

Sally Rhiannon Postlethwaite

Ezhilkani Subbian

Fernando Valle

Jonathan Vroom

John H Grate

Jeanne Bonomo Benoit

Xiyun Zhang

Robert Osborne

Smita Shankar

Kristian Karlshoej

Kaman Chan

Yoram Barak

Svetlana Balatskaya

Patricia Choudhary

The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.

Pentose fermentation by a recombinant microorganism

Genetically engineered cells and microorganisms are provided that produce fatty alcohols and fatty acids. In particular, engineered microbial cells comprise a modified native gene having &#x3b2;-ketoacyl-acp synthase activity.

Modified native beta-ketoacyl-ACP synthases and engineered microorganisms

Recombinant bacterial microorganisms are provided which comprise heterologous fatty acyl reductases ('FAR') polypeptides wherein said microorganisms have been engineered to produce increased amounts of saturated fatty alcohols and methods of making saturated fatty alcohols using the recombinant bacterial microorganisms.

Production of saturated fatty alcohols from engineered microorganisms

The invention provides variants of theCelA &#x3b2;-glucosidase that have improve &#x3b2;-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.

Method for producing an alcohol using &#x3b2;-glucosidase variant enzymes

Method of converting a biomass substrate to a fermentable sugar using a beta-glucosidase variant enzyme

Beta-glucosidase variant enzymes and related polynucleotides

Growing community of inventors

Daly City, CA, United States of America

Catherine M Cho