Elan Pharmaceuticals, Inc.

Elan Pharma International Limited

Neurex Corporation

Creagri, Inc.

Catherine M Bitler

Roberto Crea

Stephen S Bowersox

Susan D Demo

William A Horne

Mei Zhou

Anke Meyer-Franke

Paul L Wood

Tokuko Saito Wiedemann

Mohamed A Khan

Paul Wood

Fujio Numano

Duran T Anstine

Qi Zhao

Tokuko S Wiedemann

Compositions obtained from vegetation water from olives and methods for treating patients suffering from an inflammatory skin disease with the compositions are described. Included are hydroxytyrosol rich compounds obtained from olive vegetation water.

Vegetation water composition for treatment of inflammatory skin conditions

Compounds, pharmaceutical compositions, and methods of use are described which are effective in inhibiting cell death, particularly apoptotic cell death. The compositions may be used for prevention and treatment of injuries associated with cell death, including ischemia, such as results from stroke or myocardial infarction, trauma, neurodegeneration, and inflammation.

Bis-benzimidazole compounds and analogs thereof for inhibiting cell death

A method of screening for and treating subjects with a therapeutically effective amount of a compound that is effective in reducing cellular damage related to an ischemic condition, such as stroke or glaucoma. Test compounds are selected and therapeutically effective amount determined based on the relative efficacy of test compounds in preventing cell death in primary cultures of excitable cells, such as retinal ganglion cells, in vitro.

Method for selecting compounds for treating ischemia-related cellular damage

Bax-.omega. polynucleotides and polypeptides, and compositions effective to hybridize to Bax-.omega. polynucleotides are disclosed. Also disclosed are methods for altering apoptosis in cells, for promoting cell survival and for identifying compounds capable of affecting the binding of Bax-.omega. to other proteins involved in apoptosis.

Bax .omega. protein and methods

Bax omega protein and methods

Growing community of inventors

Menlo Park, CA, United States of America

Catherine M Bitler