Foundation Nationale De Transfusion Sanguine

Catherine Leberre

Henri Renon

Gilles Beaudoin

Brigitte Roche

Pierre Colinart

Alain Faure

This invention relates to a process for continuously fractionating plant, animal or human proteins by selective precipitation of the proteins resulting from placing a solution of proteins in contact with a precipitating agent constituted by a fatty acid of 6 to 14 carbon atoms, such as caprylic acid, is characterized in that respective deliveries of fatty acid and of the protein solution are continuously placed in contact in a mixing chamber of small volume with respect to the deliveries, creating a strong stirring in this mixing chamber; the individual deliveries of fatty acid and of protein solution are adjusted to controlled pH and temperature so as to maintain their ratio equal to a predetermined value; the mixture is then allowed to evolve during a phase of maturation so as to form a suspension; this suspension is separated into a liquid part from which are extracted the proteins having remained soluble, and a solid part containing proteins of different nature; and the parameters intervening in the process, such as delivery, pressure, temperature, pH, resistivity, are permanently monitored. The invention also relates to an installation for carrying out said process.

Growing community of inventors

Lanorville, France

Catherine Leberre