Adir Et Compagnie

Lonza Inc.

Lonza Ag

Catherine Caubere

Pierre Renard

Gerard Adam

Paul J Caubere

Thomas Zimmermann

Knut Burgdorf

Cristiana Boraschi

Brigitte Jamart-Gregoire

Jean-Guy Bizot-Espiard

Dominique Manechez

Catherine Nguyen

New microorganisms with plasmids stable relative to betaine use. These new microorganisms contain (a) a hybrid plasmid with a DNA fragment that contains a genetic sequence that codes for the use of betaine and (b) a mutation in the chromosomal gene coding for the betaine use.

Microorganisms for the stabilization of plasmids

New microorganisms with plasmids stable relative to betaine utilization. These new microorganisms contain (a) a hybrid plasmid with a DNA fragment that contains a genetic sequence that codes for betaine utilization and (b) a mutation in the chromosomal gene coding for the betaine utilization.

A compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3 and A are as defined in the description.

(Thia) cycloalkyl[B]indole compounds as anti-inflammatory agents

The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3 and A are as defined in the description, and medicinal product containing the same in order to treat a mammal afflicted with a peroxydation phenomenom.

(Thia)cycloalkyl[B]indoles

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Nancy, France

Catherine Caubere