The Dow Chemical Company

Catherine A Alexander

Norton P Peet

Robert J Cregge

6-[(Cyclic amino)alkylamino]-7,8,9,10-tetrahydro-1,2,4-triazolo[3,4-a]phthalazines are novel compounds prepared by the reaction of a 6-halo-7,8,9,10-tetrahydro-1,2,4-triazolo[3,4-a]phthalazine with an appropriate (cyclic amino)alkylamine. The compounds are useful as bronchodilators.

6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines

Substituted tetrahydroimidazo[2,1-a]phthalazine compounds such as 6-methylamino-7,8,9,10-tetrahydroimidazo[2,1-a]phthalazine are prepared by reacting a 6-halo-7,8,9,10-tetrahydroimidazo[1,2-a]phthalazine with an appropriate amine. The compounds are useful as bronchodilators.

6-Substituted tetrahydroimidazo[2,1-a]phthalazines and use as

Substituted tetrahydropyridazino[1,6-a]benzimidazole compounds such as 2-methylamino-6,7,8,9-tetrahydropyridazino[1,6-a]benzimidazole are prepared by reacting a 2-halo-6,7,8,9-tetrahydropyridazino[1,6-a]benzimidazole with an appropriate amine. The compounds are useful as bronchodilators.

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Indianapolis, IN, United States of America

Catherine A Alexander