Lumitex, Inc.

Carolyn Guzik

Alan Greszler

Michael Kerns

Timothy Orr

Dinusha Thotagamuwa

The present disclosure provides a method for treating ischemic stroke by illuminating a skin surface to reduce free radical generation in subsurface target tissues (e.g., the brain following an ischemic event). The method utilizes a waveguide that receives light from a light source. The waveguide is placed adjacent a skin surface of a patient and the waveguide emits light that passes through the skin surface and illuminates a subsurface target tissue. The waveguide includes light-extracting features configured to emit light at a target angle relative to the surface tissue. That is, the light-extracting features alter a trajectory of light emitted by the waveguide, such that a larger percentage of light emitted by the light guide has an angle that is +/−25 degrees off of a center line of the light guide.

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Avon, OH, United States of America

Carolyn Guzik