Anacor Pharmaceuticals, Inc.

Carolyn Bellinger-Kawahara

Kirk R Maples

Jacob J Plattner

Yong-Kang Zhang

Tsutomu Akama

Stephen J Baker

Vincent S Hernandez

Virginia J Sanders

Karin M Hold

Yvonne Freund

Huchen Zhou

James J Leyden

Stephen J Benkovic

Rajeshwar Singh

Ving J Lee

Vittorio A Sauro

David Perry

Jocob J Plattner

Karin Hold

Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.

Boron-containing small molecules as anti-inflammatory agents

This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.

Boron-containing small molecules

Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

Hydrolytically-resistant boron-containing therapeutics and methods of use

Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

Methods of treating and/or preventing surface infections, such as acne, in an animal, such as a human being, using antibiotics incorporating borinic acid complexes, especially picolinic acid derivatives, are disclosed, along with compositions of these antibiotics.

Boron-containing compounds and methods of use

Compositions and methods of use of borinic acid complexes, especially hydroxyquinoline, imidazole and picolinic acid derivatives, as anti-viral agents as well as therapeutic agents for the treatment of diseases caused by viruses are described.

Anti-viral uses of borinic acid complexes

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Redwood City, CA, United States of America

Carolyn Bellinger-Kawahara