Medtronic, Inc.

Alza Corporation

Carolann M Holmblad

Allan H Jevne

Joseph B Phipps

Warren W Howland

Patrick T Cahalan

James R Keogh

Maura G Donovan

Brett R Vegoe

Terese A Bartlett

Joan M Bergstrom

Robert W Pike, Jr

Eileen L Schultz

A wound dressing for use with exuding wounds includes (a) an outer vapor permeable layer permitting transpiration of fluid from the dressing; (b) an intermediate layer of hydrogel adapted for absorbing wound exudate; (c) a wound-contacting layer for separating the intermediate hydrogel layer from the wound; (d) wicking means associated with the wound-contacting layer for conducting exudate from the wound to the hydrogel; and (e) a therapeutic agent retained in the dressing by the wound-contacting layer.

Absorptive wound dressing for wound healing promotion

An iontophoretic device having a two-layer active electrode element is disclosed. The active element is composed of overlapping skin contact hydrogel and carrier layers. The carrier layer contains dispersed or dissolved active agent. The active electrode element maintains the active agent in stable form and permits efficient transport of the active agent to the host. Also disclosed is an iontophoretic device having a single layer active electrode element. The single layer is a hydrogel as manufactured or substantially dry and capable of being hydrated before use. The skin contact hydrogel of the two-layer active electrode element preferably.

Device and method for iontophoretic drug delivery

Amphoteric N-substituted acrylamide hydrogel and method

Novel hydrogel formulations useful as adhesive reservoirs for topical or transdermal drugs employ as the polymer base a crosslinked polymer or copolymer of 2-acrylamido-2-methylpropanesulfonic acid or a salt thereof. The gels are prepared from polymerizable compositions comprising:

Hydrophilic pressure sensitive adhesive for topical administration of

A method of fabricating prosthesis material having a conduit configuration.

Method for fabricating prosthesis material

Novel, hydrophilic, skin-compatible, pressure sensitive, solid, adhesive gel hydrogel composition comprising 25 to 50 weight percent polyvinyl pyrolidone (PVP) preferably having a molecular weight in the range of about 100,000 to 600,000, 2 to 5 weight percent polyvinyl alcohol (PVA) preferably having a molecular weight in the range of about 150,000 to 300,000, about 5 to about 40 weight percent humectant, about 3 to about 50 weight percent water, about 0 to about 50 weight percent of an ionic species. In a preferred aspect, the composition of the invention is utilized in an iontophoresis device to provide a hydrophilic gel matrix from which a drug is iontophoretically delivered.

Hydrophilic pressure sensitive biomedical adhesive composition

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Cambridge, MN, United States of America

Carolann M Holmblad