Medtronic, Inc.

Medtronic Cv Luxembourg S.a.r.l.

Medtronic Vascular, Inc.

Medtronics, Inc.

Carol Elsa Eberhardt

Janice Lynn Shay

Timothy R Ryan

Charles P Tabor

Joseph C Morrow

Timothy G Laske

Mark J Capps

Brian A Glynn

Billie J Millwee

Anne L Brody Rubin

Alexander J Hill

Carolyn C Majkrzak

Debra A Taitague

Faisal Kalam

Jerald Lamont Redmond

Mark T Stewart

James R Keogh

Nasser Rafiee

Tammy Y Tam

David E Francischelli

Cynthia T Clague

James R Skarda

Ana Menk

Mark J Dolan

Jack D Lemmon

Pham Lo

Gopikrishnan Soundararajan

Kshitija P Garde

Morgan House

Louis A Campbell

Benjamin Wong

Wei Wang

Laura McKinley

Tracey Tien

Elliot J Howard

Karl Olney

Mark W Torrianni

Michael J Tuchek

Luis A Salazar

David J Myers

Melissa R Young

J Michael Tuchek

Arin N Holecek

Maria Awad

Tomas McNatt

David L Kulcinski

Stuart R MacDonald

Melissa Denton

Eric Richardson

Robert A Pinkul

Tara S Kupumbati

Hussain Rangwala

Kenny Dang

Christopher G Toomes

Grant W Christie

Ann L Brody Rubin

Maria Botrous

Cynthia H Chiu

Thao M Nguyen

Taylor Winters

Tom Hessler

Mark J Capp

Thomas M Hessler

Tomas Mcnatt

Khitija Garde

Anne B Rubin

Timothy R Laske

Stuart R Macdonald

Morgan M House

A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stented valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

Stents for prosthetic heart valves

A single piece stent construction having a plurality of commissure posts, each of which extends upwardly from a solid ring along a bend line and generally along a central longitudinal axis of the stent.

Stents for prosthetic heart valves and methods of making same

A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the tubular body portion.

A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

A surgical sutureless valve that is attached to a stent frame for delivery to a location in a patient using percutaneous implantation devices and methods.

Stented prosthetic heart valves

Stent for prosthetic heart valves

A stented valve having at least one leaflet made of pericardium or other material having a relatively thin profile at the annulus. The leaflets are attached via chords to a stent frame, where the chords are positioned to mimic the native valve anatomy and functionality. In particular, the valves of one exemplary embodiment of the invention are sized to replace a mitral valve and therefore the chords are arranged to prevent prolapse of the leaflets into the atrium. The stented valve has a relatively short height at its annulus due to the positioning of the chords. In addition, the stented valve is capable of being crimped to a small enough size that it can be delivered to the implantation site via transcatheter delivery systems and methods.

Prosthetic heart valve devices and methods of valve replacement

A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.

Anti-paravalvular leakage component for a transcatheter valve prosthesis

A method for treating a human patient includes emitting ultrasound energy from an ultrasound transducer positioned remotely from target tissue of the patient. The ultrasound transducer is positioned at a desired location relative to the patient and target tissue using location and imaging techniques. The method further includes focusing the ultrasound energy such that one or more focal points are directed to the target tissue of the patient and ablating the target tissue at each focal point. The target tissue is ablated via the focused ultrasound energy without ablating non-target tissue through which the ultrasound energy passes between the ultrasound transducer and the one or more focal points.

Method for ablating target tissue of a patient

A method of reinforcing or repairing a bioprosthetic tissue for use as a prosthetic valve leaflet. The method includes evaluating a bioprosthetic tissue, identifying a defect in the bioprosthetic tissue, and selectively applying an adhesive to a surface of the bioprosthetic tissue at the defect prior to implantation in a patient.

Bioprosthetic tissue repair and reinforcement

A prosthetic stented heart valve which includes a compressible and expandable stent structure having first and second opposite ends, an expanded outer periphery, and a compressed outer periphery that is at least slightly smaller than the expanded outer periphery when subjected to an external radial force. The valve further includes a valve segment comprising a dual-layer sheet formed into a generally tubular shape having at least one longitudinally extending seam, and a plurality of leaflets formed by attachment of an outer layer of the dual-layer sheet to an inner layer of the dual-layer sheet in a leaflet defining pattern. The valve segment is at least partially positioned within the stent structure. The valve may further include at least one opening in the outer layer of the dual-layer sheet that is spaced from both the first and second ends of the stent structure.

Prosthetic cardiac valve formed from pericardium material and methods of making same

Growing community of inventors

Fullerton, CA, United States of America

Carol Elsa Eberhardt